Renal clearance ratio

The renal clearance ratio or fractional excretion is a relative measure of the speed at which a constituent of urine passes through the kidneys.[1][2] It is defined by following equation:

clearance\ ratio\ of\ X={\frac {C_{x}}{C_{in}}}

X is the analyte substance
C_x is the renal plasma clearance of X
C_in is the renal plasma clearance of inulin.

Diagram showing the basic physiologic mechanisms of the kidney

Creatinine is sometimes used instead of inulin as the reference substance.

References

Rudolfs K. Zalups; Lawrence H. Lash (1996). Methods in Renal Toxicology. CRC Press. pp. 2–3. ISBN 978-1-4398-0560-2.
Khurana (2005). Textbook Of Medical Physiology. Elsevier India. pp. 561–2. ISBN 978-81-8147-850-4.

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[ZalupsLash1996-1] Rudolfs K. Zalups; Lawrence H. Lash (1996). Methods in Renal Toxicology. CRC Press. pp. 2–3. ISBN 978-1-4398-0560-2.

[Khurana2005-2] Khurana (2005). Textbook Of Medical Physiology. Elsevier India. pp. 561–2. ISBN 978-81-8147-850-4.

Renal clearance ratio

See also

References