Spondylosis

Spondylosis is the degeneration of the vertebral column from any cause. In the more narrow sense it refers to spinal osteoarthritis, the age-related wear and tear of the spinal column, which is the most common cause of spondylosis. The degenerative process in osteoarthritis chiefly affects the vertebral bodies, the neural foramina and the facet joints (facet syndrome). If severe, it may cause pressure on the spinal cord or nerve roots with subsequent sensory or motor disturbances, such as pain, paresthesia, imbalance, and muscle weakness in the limbs.

Compare spondylopathy (hypernymic), spondylitis (partly overlapping in the broader of the two senses of "spondylosis"), spondyloarthropathy, spondylolysis, spondylolisthesis, and spinal stenosis.
Spondylosis
Thoracic spondylosis
SpecialtyNeurosurgery
Orthopedics

When the space between two adjacent vertebrae narrows, compression of a nerve root emerging from the spinal cord may result in radiculopathy (sensory and motor disturbances, such as severe pain in the neck, shoulder, arm, back, or leg, accompanied by muscle weakness). Less commonly, direct pressure on the spinal cord (typically in the cervical spine) may result in myelopathy, characterized by global weakness, gait dysfunction, loss of balance, and loss of bowel or bladder control. The patient may experience shocks (paresthesia) in hands and legs because of nerve compression and lack of blood flow. If vertebrae of the neck are involved it is labelled cervical spondylosis. Lower back spondylosis is labeled lumbar spondylosis. The term is from Ancient Greek σπόνδυλος spóndylos, "a vertebra", in plural "vertebrae – the backbone".

Signs and symptoms

Complications

A rare but severe complication of this disease is vertebrobasilar insufficiency.[1] This is a result of the vertebral artery becoming occluded as it passes up in the transverse foramen. The spinal joints become stiff in cervical spondylosis. Thus the chondrocytes which maintain the disc become deprived of nutrition and die. Secondary osteophytes may cause stenosis for spinal nerves, manifesting as radiculopathy.

Causes

Spondylosis is caused from years of constant abnormal pressure, caused by joint subluxation, stress induced by sports, acute and/or repetitive trauma, or poor posture, being placed on the vertebrae and the discs between them. The abnormal stress causes the body to form new bone in order to compensate for the new weight distribution. This abnormal weight bearing from bone displacement will cause spondylosis to occur. Poor postures and loss of the normal spinal curves can lead to spondylosis as well. Spondylosis can affect a person at any age; however, older people are more susceptible.[2]

Diagnosis
CT scan of a man presenting with radiculopathy of the left cervical spinal nerve 7. It shows spondylosis with osteophytes between the vertebral bodies C6 and C7 on the left side, causing foraminal stenosis at this level (lower arrow, also showing axial plane), explaining the symptoms. There is also spondylosis of the facet joint between C2 and C3, with some foraminal stenosis at this level (upper arrow), which appears to be asymptomatic.

There are multiple techniques used in the diagnosis of spondylosis, these are;

  • Cervical Compression Test, a variant of Spurling's test, is performed by laterally flexing the patient's head and placing downward pressure on it. Neck or shoulder pain on the ipsilateral side (i.e., the side to which the head is flexed) indicates a positive result for this test. A positive test result is not necessarily a positive result for spondylosis and as such additional testing is required.[3]
  • Lhermitte sign: feeling of electrical shock with patient neck flexion[4]
  • Reduced range of motion of the neck, the most frequent objective finding on physical examination[5]
  • MRI and CT scans are helpful for pain diagnosis but generally are not definitive and must be considered together with physical examinations and history.[5]

Treatment

Many of the treatments for cervical spondylosis have not been subjected to rigorous, controlled trials.[6] Surgery is advocated for cervical radiculopathy in patients who have intractable pain, progressive symptoms, or weakness that fails to improve with conservative therapy. Surgical indications for cervical spondylosis with myelopathy (CSM) remain somewhat controversial, but "most clinicians recommend operative therapy over conservative therapy for moderate-to-severe myelopathy".[7]

Physical therapy may be effective for restoring range of motion, flexibility and core strengthening. Decompressive therapies (i.e., manual mobilization, mechanical traction) may also help alleviate pain. However, physical therapy and osteopathy cannot "cure" the degeneration, and some people view that strong compliance with postural modification is necessary to realize maximum benefit from decompression, adjustments and flexibility rehabilitation.

Surgery

Current surgical procedures used to treat spondylosis aim to alleviate the signs and symptoms of the disease by decreasing pressure in the spinal canal (decompression surgery) and/or by controlling spine movement (fusion surgery).[8]

Decompression surgery: The vertebral column can be operated on from both an anterior and posterior approach. The approach varies depending on the site and cause of root compression. Commonly, osteophytes and portions of intervertebral disc are removed.[9]

Fusion surgery: Performed when there is evidence of spinal instability or mal-alignment. Use of instrumentation (such as pedicle screws) in fusion surgeries varies across studies.[8]

See also

References
  1. Denis, Daniel J.; Shedid, Daniel; Shehadeh, Mohammad; Weil, Alexander G.; Lanthier, Sylvain (3 September 2013). "Cervical spondylosis: a rare and curable cause of vertebrobasilar insufficiency". European Spine Journal. 23: 206–213. doi:10.1007/s00586-013-2983-2. eISSN 1432-0932. ISSN 0940-6719. OCLC 27638222. PMID 24000075. S2CID 1552821.
  2. Newman & Santiago, 2013
  3. Caridi, John M.; Pumberger, Matthias; Hughes, Alexander P. (1 October 2011). "Cervical Radiculopathy: A review". HSS Journal: The Musculoskeletal Journal of Hospital for Special Surgery. 7 (3): 265–272. doi:10.1007/s11420-011-9218-z. PMC 3192889. PMID 23024624.
  4. Lhermitte, J. J. (4 March 1920). "Les Formes douloureuses de la Commotion de la Moelle épiniére" [Painful Forms of Spinal Cord Concussion]. Revue neurologique (in French). Société Française de Neurologie. 36 (3): 257–262 – via Internet Archive.
  5. McCormack, Bruce M (1996). "Cervical Spondylosis an update". Western Journal of Medicine. 165 (1/2): 43–44. PMC 1307540. PMID 8855684.
  6. Binder, Allan I. (10 March 2007). "Cervical Spondylosis and Neck Pain". British Medical Journal. 334 (7592): 527–31. doi:10.1136/bmj.39127.608299.80. JSTOR 20506602. PMC 1819511. PMID 17347239.
  7. Baron, M. E.
  8. Gibson, J. N. Alastair; Waddell, Gordon (20 April 2005). "Surgery for degenerative lumbar spondylosis". Cochrane Database of Systematic Reviews. John Wiley & Sons (4). doi:10.1002/14651858.CD001352.pub3. eISSN 1465-1858. ISSN 1464-780X. OCLC 41878351. PMID 15846617.
  9. Malcolm, George (1 September 2002). "Surgical disorders of the cervical spine: presentation and management of common disorders". Journal of Neurology, Neurosurgery, and Psychiatry. 73 (Suppl 1): i34–i41. doi:10.1136/jnnp.73.suppl_1.i34. eISSN 1468-330X. ISSN 0022-3050. PMC 1765596. PMID 12185260. Cervical discs or osteophytes indenting the cord anteriorly will therefore be removed by anterior cervical discectomy, whereas a narrow cervical canal secondary to hypertrophied posterior ligaments or a congenitally narrow canal will be treated by a posterior decompression.

Further reading
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