Zolimidine

Zolimidine (zoliridine, brand name Solimidin) is a gastroprotective[1] drug previously used for peptic ulcer[2] and gastroesophageal reflux disease.[3]

Zolimidine
Names
Preferred IUPAC name
2-[4-(Methanesulfonyl)phenyl]imidazo[1,2-a]pyridine
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.013.589
KEGG
PubChem CID
UNII
InChI
  • InChI=1S/C14H12N2O2S/c1-19(17,18)12-7-5-11(6-8-12)13-10-16-9-3-2-4-14(16)15-13/h2-10H,1H3 N
    Key: VSLIUWLPFRVCDL-UHFFFAOYSA-N N
  • InChI=1/C14H12N2O2S/c1-19(17,18)12-7-5-11(6-8-12)13-10-16-9-3-2-4-14(16)15-13/h2-10H,1H3
    Key: VSLIUWLPFRVCDL-UHFFFAOYAK
SMILES
  • CS(=O)(=O)C1=CC=C(C=C1)C2=CN3C=CC=CC3=N2
Properties
Chemical formula
 C14H12N2O2S
Molar mass 272.32 g/mol
Density 1.31 g/cm3
Pharmacology
A02BX10 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

See also

References
  1. Parisio, C; Clementi, F (November 1976). "Surface Alterations Induced by Stress in Gastric Mucosa: Protective Effect of Zolimidine. A Transmission and Scanning Electron Microscope Investigation". Laboratory Investigation. 35 (5): 484–95. PMID 136548.
  2. Belohlavek, D; Malfertheiner, P (1979). "The Effect of Zolimidine, Imidazopyridine-derivate, on the Duodenal Ulcer Healing". Scandinavian Journal of Gastroenterology. Supplement. 54: 44. PMID 161649.
  3. Materia, A; Basso, N; Bagarani, M; Basoli, A; Speranza, V (30 April 1981). "Treatment of Alkaline Reflux Gastritis with Zolimidine. Controlled Study". La Clinica Terapeutica. 97 (2): 183–91. PMID 6453678.


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