Report of an Expert Consultation on the Uses of Nucleic Acid Amplification Tests for the Diagnosis of Tuberculosis

(PDF - 64Kb)

This report is based on contributions of an expert panel of external consultants convened by CDC and the Association of Public Health Laboratories (D Alland MD, New Jersey Medical School; J Bernardo MD, Boston University School of Medicine; B Hanna PhD, NYU School of Medicine; RL Kaplan PhD, Quest Diagnostics; M Kawamura MD, San Francisco Department of Public Health TB Control Section; S Liska DrPH, San Francisco Public Health Laboratory; C Nivens, Missouri State Tuberculosis Laboratory; M Salfinger MD, Bureau of Laboratories, Florida Department of Health; B Seaworth MD, Heartland National TB Center, D Warshauer PhD, Wisconsin State Laboratory of Hygiene, KE Wroblewski MPH, Association of Public Health Laboratories) and CDC participants (K Castro MD, L Diem BS, J Jereb MD, P Lobue MD, S Marks MPH, J Mazurek MD, B Metchock DrPH, T Shinnick PhD, A Vernon MD, Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention).

• Background
• General Considerations
• Research Needs
• Molecular Drug Susceptibility Tests (DSTs)
• Communication Plan for New Recommendations
• General Recommendations of the Expert Panel
• Recommendations to ACET, CDC, DTBE