Colfosceril palmitate

Colfosceril palmitate
Clinical data
Trade namesExosurf
Other names[2-({[2,3-bis(hexadecanoyloxy)propyl] phosphonato}oxy)ethyl]trimethylazanium
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 2,3-di(hexadecanoyloxy)propyl 2-trimethylazaniumylethyl phosphate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.516
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Chemical and physical data
FormulaC40H80NO8P
Molar mass734.053 g·mol−1
3D model (JSmol)
SMILES
  • O=C(OCC(OC(=O)CCCCCCCCCCCCCCC)COP([O-])(=O)OCC[N+](C)(C)C)CCCCCCCCCCCCCCC
InChI
  • InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3 checkY
  • Key:KILNVBDSWZSGLL-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Colfosceril palmitate (trade name Exosurf) is a drug used as a pulmonary surfactant.[1] It is a drug that is used in surfactant deficient conditions such as infant respiratory distress syndrome in newborns.

See also

  • Dipalmitoylphosphatidylcholine

References

  1. ↑ Rubin BK (1996). "Therapeutic aerosols and airway secretions". Journal of Aerosol Medicine. 9 (1): 123–30. doi:10.1089/jam.1996.9.123. PMID 10160202.
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