Ethambutol/isoniazid

Ethambutol/isoniazid
Combination of
EthambutolAnti-tuberculosis medication
IsoniazidAnti-tuberculosis medication
Clinical data
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Pregnancy
category
  • US: C (Risk not ruled out)
    Defined daily dosenot established[1]

    Ethambutol/isoniazid is a medication used to treat tuberculosis.[2] It is a fixed dose combination of ethambutol and isoniazid.[2] It is used along with other antituberculosis medication.[2] It is taken by mouth.[2]

    Side effects are those of the underlying medications.[2] More common side effects include poor coordination, numbness, and liver problems.[3] Liver problems may be severe and are more likely in people over the age of 50.[3] Use is not recommended in children.[2] It is unclear if use in pregnancy is safe for the baby.[3]

    It was removed from the World Health Organization's List of Essential Medicines in 2019.[4] The wholesale cost in the developing world is about 1.47 to 1.99 USD a month.[5] The combination product is not available in Canada or in the United States.[3]

    Dosage

    The defined daily dose is not established[1]

    References

    1. 1 2 "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 2 August 2020. Retrieved 18 September 2020.
    2. 1 2 3 4 5 6 World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 140. hdl:10665/44053. ISBN 9789241547659.
    3. 1 2 3 4 "Ethambutol and Isoniazid Drug Information, Professional". www.drugs.com. November 1998. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
    4. World Health Organization (2019). Executive summary: the selection and use of essential medicines 2019: report of the 22nd WHO Expert Committee on the selection and use of essential medicines. Geneva: World Health Organization. hdl:10665/325773. WHO/MVP/EMP/IAU/2019.05. License: CC BY-NC-SA 3.0 IGO.
    5. "Ethambutol + Isoniazid". International Drug Price Indicator Guide. Archived from the original on 22 January 2018. Retrieved 8 December 2016.
    Identifiers:



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