Isoaminile

Isoaminile
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.000.940
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Chemical and physical data
FormulaC16H24N2
Molar mass244.382 g·mol−1
3D model (JSmol)
SMILES
  • N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C
InChI
  • InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3 checkY
  • Key:WFLSCFISQHLEED-UHFFFAOYSA-N checkY
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Isoaminile is an antitussive (cough suppressant) used under the trade-name Peracon.[1]

The normal therapeutic dose is 40–80 mg of the cyclamate salt, with a maximum of five doses in a 24-hour period. In addition to its central antitussive effects, it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.

References

  1. Chappel CI, von Seeman C (1963). "Antitussive Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 3. Butterworth. pp. 114–115. doi:10.1016/S0079-6468(08)70117-6. ISBN 978-0-444-53322-7. Retrieved 2013-09-12.
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