Haplogroup W
Haplogroup W is a human mitochondrial DNA (mtDNA) haplogroup.
Haplogroup W | |
---|---|
Possible time of origin | 23,900 ybp[1] |
Possible place of origin | Western Asia |
Ancestor | N2 |
Descendants | W1, C194T, W3, W4, W5, W6, W7 |
Defining mutations | 195 204 207 1243 3505 5460 8251 8994 11947 15884C 16292[2] |
Origin
Haplogroup W is believed to have originated around 23,900 years ago in Western Asia.[1] It is descended from the haplogroup N2.
Distribution

Haplogroup W is found in Europe, Western Asia, and South Asia.[3] It is widely distributed at low frequencies, with a high concentration in Northern Pakistan.[4] Haplogroup W is also found in the Maghreb among Algerians (1.08%-3.23%)[5] and in Siberia among Yakuts (6/423 = 1.42%[6]).
Additionally, the clade has been observed among ancient Egyptian mummies excavated at the Abusir el-Meleq archaeological site in Middle Egypt, which date from the Ptolemaic Kingdom.[7]
The W5 subclade has been found in a fossil associated with the Starčevo culture (Lánycsók site; 1/1 or 100%).[8]
Ancient DNA analysis found that the medieval individual Sungir 6 (730-850 cal BP) belonged to the W3a1 subclade.[9]
Subclades
Tree

This phylogenetic tree of haplogroup W subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[2] and subsequent published research.
- W
- W1 – Italy,[10] Poland,[11] Czech Republic, Slovenia, Finland, Spain, Qashqai people of Iran[12]
- W-C194T
- W3 - Turkey,[18] Azerbaijan,[18][19] India (Jammu and Kashmir,[18][20] Tamil Nadu[18])
- W3a
- W3a1 – Armenians,[21] Turkey[18] (Turkish,[18] Kurd[22]), France (Toulouse,[23] Sarthe[18]), Italy (Tuscany,[24] Sardinia,[25] Sicily,[26] Umbria,[27] Campania,[28] Trentino-Alto Adige[29]), Hungary,[18] Poland,[18][30] Ukraine,[18] Belarus,[18] Russia (Sunghir6 from 750 - 900 ybp Vladimir Oblast,[18] Sverdlovsk Oblast,[18] Omsk Oblast,[18] Ingushetia,[18] Volga Tatar,[18] Chechens[18]), Denmark,[18] Berbers from Morocco,[31] Pakistan (Pashtun,[18] Kho[18]), India,[18] Singapore,[18] United States[18]
- W3a1a
- W3a1a1 – Polish people, Ashkenazi Jews[32]
- W3a1a2 - Russia (Nizhny Novgorod Oblast,[18] Tatar from Buinsk[18])
- W3a1a3 - Poland (Podkarpackie[18]), United States[18]
- W3a1a+T9090C - Pakistan (Kho[18])
- W3a1a+A15325G - Italy (Napoli[18])
- W3a1b – Pakistan (Pashtuns,[18] Sindhi, Azad Kashmir[18]), India[18] (New Delhi,[33] Andhra Pradesh[18]),[34] Bangladesh (Bengali[18]), Thailand[18] (Mon, Thai), China (Shanghai[18]), United States[18] (Hispanic)
- W3a1-T199C
- W3a1c - England,[18] United States,[18] Slovakia,[18] Russia (Ryazan Oblast,[18] Tambov Oblast,[18] Bashkortostan[18]), Kazakhstan,[18] China (Daur[18][35])
- W3a1d – Hungarians,[36][37] Serbia,[38] Republika Srpska,[18] Latvia,[18] Poland,[18] Ukraine,[18] Russia (Ulyanovsk Oblast,[18] Yakuts[39][18]), New Zealand[18]
- W3a1a
- W3a2 – France (Seine-Maritime[18]), Poland,[18] India,[40][18] Uygurs from China[18]
- W3a1 – Armenians,[21] Turkey[18] (Turkish,[18] Kurd[22]), France (Toulouse,[23] Sarthe[18]), Italy (Tuscany,[24] Sardinia,[25] Sicily,[26] Umbria,[27] Campania,[28] Trentino-Alto Adige[29]), Hungary,[18] Poland,[18][30] Ukraine,[18] Belarus,[18] Russia (Sunghir6 from 750 - 900 ybp Vladimir Oblast,[18] Sverdlovsk Oblast,[18] Omsk Oblast,[18] Ingushetia,[18] Volga Tatar,[18] Chechens[18]), Denmark,[18] Berbers from Morocco,[31] Pakistan (Pashtun,[18] Kho[18]), India,[18] Singapore,[18] United States[18]
- W3b – Italy (Calabria[41]), Albania,[18] Serbia,[18] Romania (Bucharest[18]), Bulgarians,[18][42] Turkey,[18] Iraq[18] (Assyrian[43]), Iran,[18] Armenians,[44] Kurds, Tajiks (especially Wakhis and other Pamiris), Pakistan (Burusho, Kho, Makrani), Cambodia,[45] Uyghurs[18]
- W3b1 – Austrians, Ashkenazi Jews[46]
- W3a
- W4 - Denmark,[47] Poland,[48] Italy (Sardinia,[18] Umbria[49]), Pakistan (Sindhis[18]), India (Jammu and Kashmir[18][50]), Mongolia,[18][51] United Kingdom (ancient Orkney[52])
- W4a - England (St Mary Spital, pre-Black Death medieval London, ca. 725 years before present[53]), Ukraine (Russian speaker from Kharkiv Oblast[18]), India,[18] China (Xinjiang ca. 1412 - 1529 years before present[18])
- W4a1 – Finns,[54] Sweden (Dalarna County[18]), Poland (Mazowieckie[18]), Turkey,[18] England,[18] United States[18]
- W4b - Italy,[18] Mongolia[18]
- W4c - Italy,[18] Poland,[18] India[18]
- W4d - Albania,[18] Turkey (Kurds[18][55]), Iraq (Baghdad[18]), Iran (Lorestan[56]), Pakistan (Kho[57])
- W4a - England (St Mary Spital, pre-Black Death medieval London, ca. 725 years before present[53]), Ukraine (Russian speaker from Kharkiv Oblast[18]), India,[18] China (Xinjiang ca. 1412 - 1529 years before present[18])
- W5 - Denmark,[58][18] Poland,[59][18] Serbia,[60][18] Algeria[18] (Batna[61]), Morocco (Berber[62]), Iran (Persian[63]), United States[64][18]
- W5a - Germany,[18] Denmark[65][18]
- W5a1
- W5a1a – Flemish people, Norway (Rogaland[18]), Denmark,[18] Italy (Tuscany[18][66]), Canary Islands,[67] Brazil,[18] Irish people, Polish people,[68][18] Russia (Belgorod Oblast[18][69]), Canada,[18] United States[18]
- W5a1a1 - England,[18] Estonia,[18] Russia (Adyghe in Kabardino-Balkaria[18])
- W5a1a1a
- W5a1a1 - England,[18] Estonia,[18] Russia (Adyghe in Kabardino-Balkaria[18])
- W5a1a – Flemish people, Norway (Rogaland[18]), Denmark,[18] Italy (Tuscany[18][66]), Canary Islands,[67] Brazil,[18] Irish people, Polish people,[68][18] Russia (Belgorod Oblast[18][69]), Canada,[18] United States[18]
- W5a2 - United Kingdom,[18] Denmark,[18] Germany (North Rhine-Westphalia[18]), Poland[18]
- W5a2b
- W5a1
- W5b - Portugal (Azores,[18] Leiria[18])
- W5b1 - Denmark[18]
- W5b1a
- W5b1 - Denmark[18]
- W5a - Germany,[18] Denmark[65][18]
- W6 – Italy, Kuwait,[70] Persians[71] from Iran, Russia (North Ossetia,[72] Belgorod Oblast), Kazakhstan, Mongolia
- W7 – Armenians[34]
- W8 – Bedouin of Israel, Yemen, Iran
- W9
- W3 - Turkey,[18] Azerbaijan,[18][19] India (Jammu and Kashmir,[18][20] Tamil Nadu[18])
See also

Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups | |||||||||||||||||||||||||||||||||||||||
Mitochondrial Eve (L) | |||||||||||||||||||||||||||||||||||||||
L0 | L1–6 | ||||||||||||||||||||||||||||||||||||||
L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||||||||||
M | N | ||||||||||||||||||||||||||||||||||||||
CZ | D | E | G | Q | O | A | S | R | I | W | X | Y | |||||||||||||||||||||||||||
C | Z | B | F | R0 | pre-JT | P | U | ||||||||||||||||||||||||||||||||
HV | JT | K | |||||||||||||||||||||||||||||||||||||
H | V | J | T |
References
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- van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457. S2CID 27566749.
- Petraglia, Michael D.; Allchin, Bridget (2007). The Evolution and History of Human Populations in South Asia: Inter-disciplinary Studies in Archaeology, Biological Anthropology, Linguistics and Genetics. Springer Science & Business Media. p. 237. ISBN 978-1-4020-5562-1.
- Meit Metspalu et al., Most of the extant mtDNA boundaries in South and Southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans. BMC Genetics, 2004
- Asmahan Bekada; Lara R. Arauna; Tahria Deba; Francesc Calafell; Soraya Benhamamouch; David Comas (September 24, 2015). "Genetic Heterogeneity in Algerian Human Populations". PLOS ONE. 10 (9): e0138453. Bibcode:2015PLoSO..1038453B. doi:10.1371/journal.pone.0138453. PMC 4581715. PMID 26402429.; S5 Table
- Sardana A Fedorova, Maere Reidla, Ene Metspalu, et al., "Autosomal and uniparental portraits of the native populations of Sakha (Yakutia): implications for the peopling of Northeast Eurasia." BMC Evolutionary Biology 2013, 13:127. http://www.biomedcentral.com/1471-2148/13/127
- Schuenemann, Verena J.; et al. (2017). "Ancient Egyptian mummy genomes suggest an increase of Sub-Saharan African ancestry in post-Roman periods". Nature Communications. 8: 15694. Bibcode:2017NatCo...815694S. doi:10.1038/ncomms15694. PMC 5459999. PMID 28556824.
- Mark Lipson; et al. (2017). "Parallel palaeogenomic transects reveal complex genetic history of early European farmers". Nature. 551 (7680): 368–372. Bibcode:2017Natur.551..368L. doi:10.1038/nature24476. PMC 5973800. PMID 29144465. Retrieved 18 November 2017.
- Sikora, Martin; Seguin-Orlando, Andaine; Sousa, Vitor C.; Albrechtsen, Anders; Korneliussen, Thorfinn; Ko, Amy; Rasmussen, Simon; Dupanloup, Isabelle; Nigst, Philip R.; Bosch, Marjolein D.; Renaud, Gabriel; Allentoft, Morten E.; Margaryan, Ashot; Vasilyev, Sergey V.; Veselovskaya, Elizaveta V.; Borutskaya, Svetlana B.; Deviese, Thibaut; Comeskey, Dan; Higham, Tom; Manica, Andrea; Foley, Robert; Meltzer, David J.; Nielsen, Rasmus; Excoffier, Laurent; Lahr, Marta Mirazon; Orlando, Ludovic; Willerslev, Eske (2017). "Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers". Science. 358 (6363): 659–662. Bibcode:2017Sci...358..659S. doi:10.1126/science.aao1807. ISSN 0036-8075. PMID 28982795.
- Homo sapiens isolate 92_Tor793_W1 mitochondrion, complete genome GenBank: KF146272.1.
- Homo sapiens isolate poz377 haplogroup W1 mitochondrion, complete genome GenBank: MT588229.1.
- Homo sapiens haplogroup W1* mitochondrion, complete genome GenBank: KC911537.1.
- Homo sapiens isolate E8_fi_ath haplogroup W1a mitochondrion, complete genome GenBank: MN516604.1.
- Homo sapiens isolate S90_fi_ath haplogroup W1b1 mitochondrion, complete genome GenBank: MN516694.1.
- Homo sapiens haplogroup W1c mitochondrion, complete genome GenBank: KC911592.1.
- Brook, Kevin Alan (2022). The Maternal Genetic Lineages of Ashkenazic Jews. Academic Studies Press. p. 121. doi:10.2307/j.ctv33mgbcn. ISBN 978-1644699843.
- Homo sapiens isolate 1549629 mitochondrion, complete genome GenBank: JX153072.1.
- Phylogeny of mtDNA haplogroup W according to YFull
- https://www.ncbi.nlm.nih.gov/nuccore/JQ245741.1
- https://www.ncbi.nlm.nih.gov/nuccore/KX467289.1
- Homo sapiens isolate Ararat_11 haplogroup W3a1 mitochondrion, complete genome GenBank: MF362752.1.
- https://www.ncbi.nlm.nih.gov/nuccore/JQ245760.1
- https://www.ncbi.nlm.nih.gov/nuccore/KF146276.1
- Homo sapiens isolate 94_Tor782_W3a1 mitochondrion, complete genome GenBank: KF146273.1.
- https://www.ncbi.nlm.nih.gov/nuccore/KF146274.1
- https://www.ncbi.nlm.nih.gov/nuccore/KY399203.1
- https://www.ncbi.nlm.nih.gov/nuccore/MN687271.1
- https://www.ncbi.nlm.nih.gov/nuccore/KF146275.1
- https://www.ncbi.nlm.nih.gov/nuccore/KY399175.1
- https://www.ncbi.nlm.nih.gov/nuccore/MH120427.1
- Homo sapiens isolate 105_Tor769_W3a1 mitochondrion, complete genome GenBank: KF146277.1.
- Brook, Kevin Alan (2022). The Maternal Genetic Lineages of Ashkenazic Jews. Academic Studies Press. p. 122. doi:10.2307/j.ctv33mgbcn. ISBN 978-1644699843.
- https://www.ncbi.nlm.nih.gov/nuccore/KF146278.1
- Olivieri, Anna; Pala, Maria; Gandini, Francesca; Kashani, Baharak Hooshiar; Perego, Ugo A.; Woodward, Scott R.; Grugni, Viola; Battaglia, Vincenza; Semino, Ornella; Achilli, Alessandro; Richards, Martin B.; Torroni, Antonio (31 July 2013). "Mitogenomes from Two Uncommon Haplogroups Mark Late Glacial/Postglacial Expansions from the Near East and Neolithic Dispersals within Europe". PLoS ONE. 8 (7): e70492. doi:10.1371/journal.pone.0070492. PMC 3729697. PMID 23936216.
- https://www.ncbi.nlm.nih.gov/nuccore/ON127719.1
- Homo sapiens haplogroup W3a1d mitochondrion, complete genome GenBank: KY849398.1.
- https://www.ncbi.nlm.nih.gov/nuccore/MG952809.1
- Homo sapiens isolate 257_Sb haplogroup W3a1d mitochondrion, complete genome GenBank: MK617275.1.
- Duggan AT, Whitten M, Wiebe V, Crawford M, Butthof A, et al. (2013), "Investigating the Prehistory of Tungusic Peoples of Siberia and the Amur-Ussuri Region with Complete mtDNA Genome Sequences and Y-chromosomal Markers." PLoS ONE 8(12): e83570. doi:10.1371/journal.pone.0083570
- Palanichamy, Malliya Gounder; Mitra, Bikash; Zhang, Cai-Ling; Debnath, Monojit; Li, Gui-Mei; Wang, Hua-Wei; Agrawal, Suraksha; Chaudhuri, Tapas Kumar; Zhang, Ya-Ping (June 2015). "West Eurasian mtDNA lineages in India: an insight into the spread of the Dravidian language and the origins of the caste system". Human Genetics. 134 (6): 637-647. doi:10.1007/s00439-015-1547-4. PMID 25832481.
- https://www.ncbi.nlm.nih.gov/nuccore/JX153106.1
- Homo sapiens haplogroup W3b mitochondrion, complete genome GenBank: MG910309.1.
- https://www.ncbi.nlm.nih.gov/nuccore/MK217237.1
- Homo sapiens isolate Artsakh_54 haplogroup W3b mitochondrion, complete genome GenBank: MF362844.1.
- https://www.ncbi.nlm.nih.gov/nuccore/KT587614.1
- Brook, Kevin Alan (2022). The Maternal Genetic Lineages of Ashkenazic Jews. Academic Studies Press. p. 123. doi:10.2307/j.ctv33mgbcn. ISBN 978-1644699843.
- https://www.ncbi.nlm.nih.gov/nuccore/KF162747.1
- https://www.ncbi.nlm.nih.gov/nuccore/OR438599.1
- https://www.ncbi.nlm.nih.gov/nuccore/MN687263.1
- https://www.ncbi.nlm.nih.gov/nuccore/KX467287.1
- https://www.ncbi.nlm.nih.gov/nuccore/OL619847.1
- https://www.ncbi.nlm.nih.gov/nuccore/MZ846967.1
- https://www.ncbi.nlm.nih.gov/nuccore/MK059742.1
- Homo sapiens isolate S79_fi_ath haplogroup W4a1 mitochondrion, complete genome GenBank: MN516681.1.
- https://www.ncbi.nlm.nih.gov/nuccore/JQ245758.1
- https://www.ncbi.nlm.nih.gov/nuccore/KF146283.1
- https://www.ncbi.nlm.nih.gov/nuccore/MN595694.2
- https://www.ncbi.nlm.nih.gov/nuccore/KF161512.1
- https://www.ncbi.nlm.nih.gov/nuccore/MH120645.1
- https://www.ncbi.nlm.nih.gov/nuccore/MK134276.1
- https://www.ncbi.nlm.nih.gov/nuccore/OQ884865.1
- https://www.ncbi.nlm.nih.gov/nuccore/KF146285.1
- https://www.ncbi.nlm.nih.gov/nuccore/KC911419.1
- https://www.ncbi.nlm.nih.gov/nuccore/MZ387785.1
- https://www.ncbi.nlm.nih.gov/nuccore/JX153386.1
- https://www.ncbi.nlm.nih.gov/nuccore/KF146284.1
- García-Olivares, Víctor; Rubio-Rodríguez, Luis A.; Muñoz-Barrera, Adrián; Díaz-de Usera, Ana; Jáspez, David; Iñigo-Campos, Antonio; Rodríguez Pérez, María Del Cristo; Cabrera de León, Antonio; Lorenzo-Salazar, José M.; González-Montelongo, Rafaela; Cabrera, Vicente M.; Flores, Carlos (20 January 2023). "Digging into the admixture strata of current-day Canary Islanders based on mitogenomes". iScience. 26 (1): 105907. doi:10.1016/j.isci.2022.105907. PMC 9840145. PMID 36647378.
- Homo sapiens haplogroup W5a1a mitochondrion, complete genome GenBank: KX518741.1.
- https://www.ncbi.nlm.nih.gov/nuccore/KY671123.1
- Homo sapiens isolate 188_Tor779_W6 mitochondrion, complete genome GenBank: KF146287.1.
- Homo sapiens haplogroup W6 mitochondrion, complete genome GenBank: KC911449.1.
- Homo sapiens isolate NOS10 mitochondrion, complete genome GenBank: JQ245723.1.
- Homo sapiens isolate 205_Tor786_W6b mitochondrion, complete genome GenBank: KF146290.1.
- Homo sapiens haplotype W6c1a mitochondrion, complete genome GenBank: KX363871.1.
- Homo sapiens haplotype W6c mitochondrion, complete genome GenBank: KF553923.1.
- Homo sapiens isolate 32_Mu mitochondrion, complete genome GenBank: MK491385.1.