KRT71

KRT71
Identifiers
Aliases	KRT71, HYPT13, K6IRS1, KRT6IRS, KRT6IRS1, keratin 71
External IDs	OMIM: 608245 MGI: 1861586 HomoloGene: 88864 GeneCards: KRT71
Gene location (Human)
Chr.	Chromosome 12 (human)[1]
End	52,553,145 bp[1]
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)[2]
End	101,651,544 bp[2]
RNA expression pattern
	Top expressed in
	nipple; ; skin of abdomen; ; right lung; ; spinal cord; ; human musculoskeletal system; ; muscular system; ; muscle; ; blood; ; mesencephalon; ; substantia nigra;
	Top expressed in
	lip; ; hair follicle; ; skin of back; ; skin of abdomen; ; secondary oocyte; ; sexually immature organism; ; conjunctival fornix; ; cornea; ; lower respiratory tract; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; structural molecule activity;
Cellular component	cytoplasm; keratin filament; extracellular exosome; cytoskeleton; intermediate filament; cytosol;
Biological process	intermediate filament organization; hair follicle morphogenesis; keratinization; cornification;
	Sources:Amigo / QuickGO
Orthologs
	112802
	56735
	ENSG00000139648
	ENSMUSG00000051879
	Q3SY84
	Q9R0H5
	NM_033448
	NM_019956
	NP_258259
	NP_064340
	Wikidata
View/Edit Human	View/Edit Mouse

KRT71 is a keratin gene. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins.[5][6] This gene encodes a protein that is expressed in the inner root sheath of hair follicles.[6] The type II keratins are clustered in a region of chromosome 12q13.[6][7]

References

GRCh38: Ensembl release 89: ENSG00000139648 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000051879 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Ho, Minh; Thompson, Brian; Fisk, Jeffrey Nicholas; Nebert, Daniel W.; Bruford, Elspeth A.; Vasiliou, Vasilis; Bunick, Christopher G. (2022-01-06). "Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders". Human Genomics. 16 (1): 1. doi:10.1186/s40246-021-00374-9. ISSN 1479-7364. PMC 8733776. PMID 34991727.
Schweizer, Jürgen; Bowden, Paul E.; Coulombe, Pierre A.; Langbein, Lutz; Lane, E. Birgitte; Magin, Thomas M.; Maltais, Lois; Omary, M. Bishr; Parry, David A. D.; Rogers, Michael A.; Wright, Mathew W. (2006-07-17). "New consensus nomenclature for mammalian keratins". The Journal of Cell Biology. 174 (2): 169–174. doi:10.1083/jcb.200603161. ISSN 0021-9525. PMC 2064177. PMID 16831889.
"Gene symbol report | HUGO Gene Nomenclature Committee". www.genenames.org. Retrieved 2023-05-01.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000139648 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000051879 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Ho, Minh; Thompson, Brian; Fisk, Jeffrey Nicholas; Nebert, Daniel W.; Bruford, Elspeth A.; Vasiliou, Vasilis; Bunick, Christopher G. (2022-01-06). "Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders". Human Genomics. 16 (1): 1. doi:10.1186/s40246-021-00374-9. ISSN 1479-7364. PMC 8733776. PMID 34991727.

[:0-6] Schweizer, Jürgen; Bowden, Paul E.; Coulombe, Pierre A.; Langbein, Lutz; Lane, E. Birgitte; Magin, Thomas M.; Maltais, Lois; Omary, M. Bishr; Parry, David A. D.; Rogers, Michael A.; Wright, Mathew W. (2006-07-17). "New consensus nomenclature for mammalian keratins". The Journal of Cell Biology. 174 (2): 169–174. doi:10.1083/jcb.200603161. ISSN 0021-9525. PMC 2064177. PMID 16831889.

[7] "Gene symbol report | HUGO Gene Nomenclature Committee". www.genenames.org. Retrieved 2023-05-01.