TNFRSF12A

Tumor necrosis factor receptor superfamily member 12A also known as the TWEAK receptor (TWEAKR) is a protein that in humans is encoded by the TNFRSF12A gene.[5][6][7]

TNFRSF12A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTNFRSF12A, CD266, FN14, TWEAKR, tumor necrosis factor receptor superfamily member 12A, TNF receptor superfamily member 12A
External IDsOMIM: 605914 MGI: 1351484 HomoloGene: 8451 GeneCards: TNFRSF12A
Orthologs
SpeciesHumanMouse
Entrez

51330

27279

Ensembl

ENSG00000006327

ENSMUSG00000023905

UniProt

Q9NP84

Q9CR75

RefSeq (mRNA)

NM_016639

NM_001161746
NM_013749

RefSeq (protein)

NP_057723

NP_001155218
NP_038777

Location (UCSC)Chr 16: 3.02 – 3.02 MbChr 17: 23.89 – 23.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000006327 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000023905 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Feng SL, Guo Y, Factor VM, Thorgeirsson SS, Bell DW, Testa JR, Peifley KA, Winkles JA (Jun 2000). "The Fn14 Immediate-Early Response Gene Is Induced During Liver Regeneration and Highly Expressed in Both Human and Murine Hepatocellular Carcinomas". Am J Pathol. 156 (4): 1253–61. doi:10.1016/S0002-9440(10)64996-6. PMC 1876890. PMID 10751351.
  6. Meighan-Mantha RL, Hsu DK, Guo Y, Brown SA, Feng SL, Peifley KA, Alberts GF, Copeland NG, Gilbert DJ, Jenkins NA, Richards CM, Winkles JA (Jan 2000). "The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration". J Biol Chem. 274 (46): 33166–76. doi:10.1074/jbc.274.46.33166. PMID 10551889.
  7. "Entrez Gene: TNFRSF12A tumor necrosis factor receptor superfamily, member 12A".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.