Azosemide

Azosemide is a high-ceiling loop diuretic agent that was brought to market in 1981 by Boehringer Mannheim.[1][2] As of 2015 it was available as a generic in some Asian countries.[3]

Azosemide
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
  • none
Identifiers
IUPAC name
  • 2-chloro-5-(2H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.044.121
Chemical and physical data
FormulaC12H11ClN6O2S2
Molar mass370.83 g·mol−1
3D model (JSmol)
SMILES
  • O=S(=O)(N)c2c(Cl)cc(c(c1n[nH]nn1)c2)NCc3sccc3
InChI
  • InChI=1S/C12H11ClN6O2S2/c13-9-5-10(15-6-7-2-1-3-22-7)8(12-16-18-19-17-12)4-11(9)23(14,20)21/h1-5,15H,6H2,(H2,14,20,21)(H,16,17,18,19) Y
  • Key:HMEDEBAJARCKCT-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)


Azosemide has been found as an adulterant in ketamine.[4]

References
  1. Sittig M (1988). Pharmaceutical Manufacturing Encyclopedia (PDF). Vol. 1. Noyes Publications. p. 122. ISBN 978-0-8155-1144-1. Archived from the original (PDF) on 2007-10-23.
  2. Bormann D (January 1980). "Diuretics". In Hess HJ (ed.). Annual Reports in Medicinal Chemistry. Vol. 15. Academic Press. pp. 100–105 (101). ISBN 978-0-08-058359-4.
  3. "International listings for azosemide". Drugs.com. Retrieved 23 July 2015.
  4. "Drug Checking Report 2011" (PDF). Energy Control. Retrieved 20 January 2022.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.