Polythiazide

Polythiazide is a thiazide diuretic.[1][2] A diuretic is any substance that promotes the production of urine.

Polythiazide
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa601101
ATC code
Identifiers
IUPAC name
  • 6-chloro-2-methyl-3-{[(2,2,2-trifluoroethyl)thio]methyl}-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.005.881
Chemical and physical data
FormulaC11H13ClF3N3O4S3
Molar mass439.87 g·mol−1
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References
  1. O'Brien ET, MacKinnon J (October 1972). "Propranolol and polythiazide in treatment of hypertension". British Heart Journal. 34 (10): 1042–4. doi:10.1136/hrt.34.10.1042. PMC 458544. PMID 5086971.
  2. Monroy A, Plata C, Hebert SC, Gamba G (July 2000). "Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction". American Journal of Physiology. Renal Physiology. 279 (1): F161-9. doi:10.1152/ajprenal.2000.279.1.f161. PMID 10894798.
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