Lipoblastomatosis

Benign lipoblastomatosis is a tumor consisting of fetal-embryonal adipocytes, frequently confused with a liposarcoma, affecting exclusively infants and young children, with approximately 90% of cases occurring before 3 years of age.[2][3]^: 626 The term lipoblastomatosis was first used by Vellios et al. in 1958, at which point the tumor became generally accepted as a distinctive entity.[4][5] Today Diffuse lipoblastoma is the preferred term for Lipoblastomatosis.[6][7] The tumor is rare, accounting for less than 1% of all childhood neoplasm,[8] and it has been found to be more common in males than females.[9][8] It often presents as an asymptomatic rapidly enlarging mass, occurring more often in the soft tissues of the extremities.[8][9]