Oxidized cellulose

Oxidized cellulose is a water-insoluble derivative of cellulose. It can be produced from cellulose by the action of an oxidizing agent, such as chlorine, hydrogen peroxide, peracetic acid, chlorine dioxide, nitrogen dioxide, persulfates, permanganate, dichromate-sulfuric acid, hypochlorous acid, hypohalites or periodates and a variety of metal catalysts.[1] Oxidized cellulose may contain carboxylic acid, aldehyde, and/or ketone groups, in addition to the original hydroxyl groups of the starting material, cellulose, depending on the nature of the oxidant and reaction conditions.[2]

Oxidized cellulose
Clinical data
ATC code
Identifiers
ChemSpider
  • none
UNII
 NY (what is this?)  (verify)

It is an antihemorrhagic.[3] It works both by absorbing the blood (similar to a cotton ball)[4] and by triggering the contact activation system. It is poorly absorbed and may cause healing complications postoperatively.[5]

See also
  • Regenerated cellulose

References
  1. Collinson, Simon; Thielemans, Wim (2010). "The catalytic oxidation of biomass to new materials focusing on starch, cellulose and lignin" (PDF). Coordination Chemistry Reviews. 254 (15–16): 1854–1870. doi:10.1016/j.ccr.2010.04.007.
  2. "Oxidized cellulose".
  3. Oto A, Remer EM, O'Malley CM, Tkach JA, Gill IS (June 1999). "MR characteristics of oxidized cellulose (Surgicel)". AJR Am J Roentgenol. 172 (6): 1481–4. doi:10.2214/ajr.172.6.10350276. PMID 10350276.
  4. "Oxidised Cellulose". Advanced Medical Solutions Group plc.
  5. Resnik, Randolph R. (2018). "Intraoperative Complications". Misch's Avoiding Complications in Oral Implantology. pp. 267–293. doi:10.1016/B978-0-323-37580-1.00007-X. ISBN 9780323375801.


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