Clindamycin/tretinoin

Clindamycin/tretinoin
Combination of
Clindamycin phosphateAntibiotic
TretinoinTopical retinoid
Clinical data
Trade namesZiana, Veltin, others
MedlinePlusa609005
License data
Routes of
administration		Topical
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
KEGG
  (verify)

Clindamycin/tretinoin is a topical gel used in the treatment of acne. The two active ingredients are the antibiotic clindamycin phosphate (1.2%) and tretinoin (0.025%), a retinoid.[1] The two active ingredients perform different functions, the clindamycin is active against gram-positive bacteria, including streptococci and penicillin-resistant staphylococci.[2] The Tretinoin element acts to reduce the amount of oil released by oil glands in skin as well as encouraging skin cell replenishment.[3] The topical treatment is stored in 2, 30, and 60 gram tubes and should be stored at 25°C (77°F), with the tube tightly shut away from light.[4] Side effects may include peeling, redness, dryness, itching and photosensitivity. Also, topical clindamycin may rarely cause diarrhea or colitis. Sun exposure while using this preparation can cause skin irritation.

Citations

  1. ↑ "Ziana Gel". Retrieved 2008-11-16.
  2. ↑ "BNF is only available in the UK". NICE. Retrieved 2021-10-05.
  3. ↑ Zasada M, Budzisz E (August 2019). "Retinoids: active molecules influencing skin structure formation in cosmetic and dermatological treatments". Postepy Dermatologii I Alergologii. 36 (4): 392–397. doi:10.5114/ada.2019.87443. PMC 6791161. PMID 31616211.
  4. ↑ "ZIANA Prescribing Information" (PDF). Archived from the original (PDF) on 2007-06-17. Retrieved 2008-11-15.
This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.