Tretinoin/benzoyl peroxide

Tretinoin/benzoyl peroxide
Combination of
TretinoinRetinoid
Benzoyl peroxideOxidizing agent
Clinical data
Trade namesTwyneo
Other namesS6G5T-3
License data
Routes of
administration
Topical
ATC code
Legal status
Legal status

Tretinoin/benzoyl peroxide, sold under the brand name Twyneo, is a fixed-dose combination medication used for the treatment of acne.[1][2] It contains tretinoin, a vitamin A derivative, and benzoyl peroxide, an oxidizing agent.[3]

The combination was approved for medical use in the United States in July 2021.[2][4][5]

References

  1. 1 2 "Twyneo (tretinoin and benzoyl peroxide) cream, for topical use" (PDF). U.S. Food and Drug Administration.
  2. 1 2 "Sol-Gel Technologies Announces FDA Approval of Twyneo" (Press release). Sol-Gel Technologies Ltd. 27 July 2021. Retrieved 27 July 2021 via GlobeNewswire.
  3. Ochsendorf F (June 2015). "Clindamycin phosphate 1.2% / tretinoin 0.025%: a novel fixed-dose combination treatment for acne vulgaris". Journal of the European Academy of Dermatology and Venereology. 29 Suppl 5: 8–13. doi:10.1111/jdv.13185. PMID 26059820. S2CID 29681121.
  4. "Twyneo: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Retrieved 27 July 2021.
  5. "NDA Approval: Twyneo" (PDF). U.S. Food and Drug Administration. 26 July 2021.


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