Monoethanolamine oleate

Ethanolamine Oleate
Clinical data
AHFS/Drugs.com	Multum Consumer Information
ATC code	C05BB01 (WHO) ;
Identifiers
	IUPAC name 2-Hydroxyethylammonium oleate;
CAS Number	2272-11-9 ;
PubChem CID	5282489;
DrugBank	DB06689 ;
ChemSpider	4445632 ;
UNII	U4RY8MRX7C;
KEGG	D02276 ;
CompTox Dashboard (EPA)	DTXSID8023008 ;
ECHA InfoCard	100.017.163
Chemical and physical data
Formula	C20H41NO3
Molar mass	343.552 g·mol−1
Density	0.974 g/cm3
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Monoethanolamine oleate (properly ethanolammonium oleate) is an antivaricose agent. It is a salt formed by Lowry–Brønsted acid–base reaction between monoethanolamine and oleic acid, is systematically named 2-hydroxyethylammonium (9Z)-octadecenoate, and has a structural formula [CH₃(CH₂)₇CH=CH(CH₂)₇CO₂][H₃NCH₂CH₂OH]. It is injected topically into varicosities to cause sclerosis (closure) of the abnormal vein.

Uses

Ethanolamine Oleate (Ethanolamin) injection is indicated for the treatment of patients with esophageal varices that have recently bled, to prevent rebleeding.

Ethanolamin is not indicated for the treatment of patients with esophageal varices that have not bled. There is no evidence that treatment of this population decreases the likelihood of bleeding.

Sclerotherapy with Ethanolamin has no beneficial effect upon portal hypertension, the cause of esophageal varices, so that recanalization and collateralization may occur, necessitating reinjection.^[1]

References

↑ "Ethanolamine Oleate". RXList. Retrieved 7 March 2020.

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[1] "Ethanolamine Oleate". RXList. Retrieved 7 March 2020.

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