IFNAR1
IFNAR1 (Interferon alpha and beta receptor subunit 1) هوَ بروتين يُشَفر بواسطة جين IFNAR1 في الإنسان.[1][2]
الوظيفة
المراجع
- "The human interferon alpha/beta receptor: characterization and molecular cloning"، Cell، 77 (3): 391–400، يونيو 1994، doi:10.1016/0092-8674(94)90154-6، PMID 8181059.
- "Entrez Gene: IFNAR1 interferon (alpha, beta and omega) receptor 1"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- "Introns in sequence tags"، Nature، 357 (6377): 367–8، 1992، doi:10.1038/357367a0، PMID 1350660.
- Qiujing Yu, Yuliya V Katlinskaya وآخرون (2015)، "DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function"، Cell Reports، 11: 785–797، doi:10.1016/j.celrep.2015.03.069، PMC 4426031، PMID 25921537.
- "The structure of the human interferon alpha/beta receptor gene"، J. Biol. Chem.، 267 (4): 2802–9، 1992، PMID 1370833.
- "Human interferon omega (omega) binds to the alpha/beta receptor"، J. Biol. Chem.، 266 (30): 19875–7، 1991، PMID 1834641.
- "Assignment of the human interferon-alpha receptor gene to chromosome 21q22.1 by in situ hybridization"، J. Interferon Res.، 10 (5): 515–7، 1990، doi:10.1089/jir.1990.10.515، PMID 2148760.
- "Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA"، Cell، 60 (2): 225–34، 1990، doi:10.1016/0092-8674(90)90738-Z، PMID 2153461.
- "Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase"، Mol. Cell. Biol.، 14 (12): 8133–42، 1994، doi:10.1128/mcb.14.12.8133، PMC 359352، PMID 7526154.
- "Interaction of the transcriptional activator Stat-2 with the type I interferon receptor"، J. Biol. Chem.، 270 (42): 24627–30، 1995، doi:10.1074/jbc.270.42.24627، PMID 7559568.
- "Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signaling"، J. Biol. Chem.، 270 (37): 21606–11، 1995، doi:10.1074/jbc.270.37.21606، PMID 7665574.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides"، Gene، 138 (1–2): 171–4، 1994، doi:10.1016/0378-1119(94)90802-8، PMID 8125298.
- "Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein"، EMBO J.، 15 (5): 1064–74، 1996، PMC 450004، PMID 8605876.
- "Direct association of STAT3 with the IFNAR-1 chain of the human type I interferon receptor"، J. Biol. Chem.، 271 (14): 8057–61، 1996، doi:10.1074/jbc.271.14.8057، PMID 8626489.
- "A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor"، EMBO J.، 16 (2): 260–6، 1997، doi:10.1093/emboj/16.2.260، PMC 1169633، PMID 9029147.
- "Post-translational up-regulation of the cell surface-associated alpha component of the human type I interferon receptor during differentiation of peripheral blood monocytes: role in the biological response to type I interferon"، Eur. J. Immunol.، 27 (5): 1075–81، 1997، doi:10.1002/eji.1830270506، PMID 9174595.
- "Induction of cytokines by HIV-1 and its gp120 protein in human peripheral blood monocyte/macrophages and modulation of cytokine response during differentiation"، J. Leukoc. Biol.، 62 (1): 49–53، 1997، PMID 9225992.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library"، Gene، 200 (1–2): 149–56، 1997، doi:10.1016/S0378-1119(97)00411-3، PMID 9373149.
- "Identification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptor"، J. Biol. Chem.، 273 (31): 19495–501، 1998، doi:10.1074/jbc.273.31.19495، PMID 9677371.
- "Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1"، J. Biol. Chem.، 273 (38): 24723–9، 1998، doi:10.1074/jbc.273.38.24723، PMID 9733772.
- "Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase"، J. Biol. Chem.، 274 (45): 32507–11، 1999، doi:10.1074/jbc.274.45.32507، PMID 10542297.
بوابة الكيمياء الحيوية
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بوابة علم الأحياء
بوابة علم الأحياء الخلوي والجزيئي
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