Succinyl-CoA hydrolase

The enzyme succinyl-CoA hydrolase (EC 3.1.2.3) catalyzes the reaction

succinyl-CoA + H2O CoA + succinate
succinyl-CoA hydrolase
Identifiers
EC no.3.1.2.3
CAS no.9025-86-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is succinyl-CoA hydrolase. Other names in common use include succinyl-CoA acylase, succinyl coenzyme A hydrolase, and succinyl coenzyme A deacylase. This enzyme participates in the tricaboxylate cycle.

References

    • Gergely J, Hele P, Ramakrishnan CV (1952). "Succinyl and acetyl coenzyme A deacylases". J. Biol. Chem. 198 (1): 323–334. PMID 12999747.


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