Succinyl-CoA hydrolase
The enzyme succinyl-CoA hydrolase (EC 3.1.2.3) catalyzes the reaction
- succinyl-CoA + H2O CoA + succinate
| succinyl-CoA hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.3 | ||||||||
| CAS no. | 9025-86-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is succinyl-CoA hydrolase. Other names in common use include succinyl-CoA acylase, succinyl coenzyme A hydrolase, and succinyl coenzyme A deacylase. This enzyme participates in the tricaboxylate cycle.
References
- Gergely J, Hele P, Ramakrishnan CV (1952). "Succinyl and acetyl coenzyme A deacylases". J. Biol. Chem. 198 (1): 323–334. PMID 12999747.
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