Adipiodone

Adipiodone
Clinical data
Trade names	Cholografin, Biligrafin
Other names	3-[[6-[(3-Carboxy-2,4,6-triiodophenyl)amino]-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
ATC code	V08AC04 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 3-{5-[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido}-2,4,6-triiodobenzoic acid;
CAS Number	606-17-7 ;
PubChem CID	3739;
IUPHAR/BPS	7400;
DrugBank	DB04711 ;
ChemSpider	3608 ;
UNII	TKQ858A3VW;
KEGG	D01774 ;
ChEBI	CHEBI:31176;
ChEMBL	ChEMBL1165268 ;
CompTox Dashboard (EPA)	DTXSID6023153 ;
ECHA InfoCard	100.009.187
Chemical and physical data
Formula	C20H14I6N2O6
Molar mass	1139.767 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(Nc1c(I)c(c(I)cc1I)C(=O)O)CCCCC(=O)Nc2c(I)c(C(=O)O)c(I)cc2I;
	InChI InChI=1S/C20H14I6N2O6/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34) ; Key:FFINMCNLQNTKLU-UHFFFAOYSA-N ;
	(verify)

Adipiodone (INN, or iodipamide; trade names Cholografin and Biligrafin) is a pharmaceutical drug used as a radiocontrast agent in X-ray imaging. It was introduced in the 1950s.[1][2]

References

Hastings-James R, Glazebrook AJ (April 1955). "Cholografin". Canadian Medical Association Journal. 72 (8): 561–5. PMC 1825662. PMID 14364399.
Dilger SK, Nelson N, Venkatesh SK, Ehman EC, Fidler JL, Fletcher JG, et al. (September 2019). "Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study". Investigative Radiology. 54 (9): 572–579. doi:10.1097/RLI.0000000000000580. PMID 31261292. S2CID 195772743.

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[1] Hastings-James R, Glazebrook AJ (April 1955). "Cholografin". Canadian Medical Association Journal. 72 (8): 561–5. PMC 1825662. PMID 14364399.

[2] Dilger SK, Nelson N, Venkatesh SK, Ehman EC, Fidler JL, Fletcher JG, et al. (September 2019). "Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study". Investigative Radiology. 54 (9): 572–579. doi:10.1097/RLI.0000000000000580. PMID 31261292. S2CID 195772743.