Ioglicic acid

Ioglicic acid is a pharmaceutical drug that was used as an iodinated contrast medium for X-ray imaging, in form of its salt meglumine ioglicate. Uses included imaging of the brain,[1] the aorta and femoral arteries,[2] and the urinary system (an examination called intravenous urography).[3]

Ioglicic acid
Clinical data
ATC code
Identifiers
IUPAC name
  • 3-acetamido-2,4,6-triiodo-5-{[(methylcarbamoyl)methyl]carbamoyl}benzoic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.051.320
Chemical and physical data
FormulaC13H12I3N3O5
Molar mass670.968 g·mol−1
3D model (JSmol)
SMILES
  • Ic1c(c(I)c(c(I)c1NC(=O)C)C(=O)O)C(=O)NCC(=O)NC

It is not known to be marketed anywhere in the world in 2021.

References

  1. Skalpe IO (1983). "Enhancement with water-soluble contrast media in computed tomography of the brain and abdomen. Survey and present state". Acta Radiologica. Supplementum. 366: 72–5. PMID 6382938.
  2. Wiebe V, Straub H (1983). "Haemodynamic side effects of meglumine ioglicate, meglumine sodium ioxaglate and iohexol in aortofemoral angiography: comparison of a high-osmolar and two low-osmolar radiological contrast media". Fortschritte Auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband. 118: 78–84. PMID 6139084.
  3. Baitsch T, Beduhn D, Klink G (1983). "Double blind comparison of ioglicate and iothalamate in intravenous urography". Fortschritte Auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband. 118: 143–7. PMID 6139069.
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