DMeOB

DMeOB is a drug used in scientific research which acts as a negative allosteric modulator of the metabotropic glutamate receptor subtype mGluR5.[1]

DMeOB
Identifiers
IUPAC name
  • 1-(3-methoxyphenyl)-N-[(3-methoxyphenyl)methylideneamino]methanimine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
ECHA InfoCard100.164.778
Chemical and physical data
FormulaC16H16N2O2
Molar mass268.316 g·mol−1
3D model (JSmol)
SMILES
  • COc2cc(ccc2)C=NN=Cc1cccc(OC)c1
InChI
  • InChI=1S/C16H16N2O2/c1-19-15-7-3-5-13(9-15)11-17-18-12-14-6-4-8-16(10-14)20-2/h3-12H,1-2H3/b17-11+,18-12+ N
  • Key:FBNPHFBYHYNMHC-JYFOCSDGSA-N N
 NY (what is this?)  (verify)

References

  1. O'Brien JA, Lemaire W, Chen TB, Chang RS, Jacobson MA, Ha SN, Lindsley CW, Schaffhauser HJ, Sur C, Pettibone DJ, Conn PJ, Williams DL (September 2003). "A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5". Molecular Pharmacology. 64 (3): 731–40. doi:10.1124/mol.64.3.731. PMID 12920211.


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