Visnadine

Visnadine (or visnadin) is a natural vasodilator.[1] It was first isolated from bishop's weed (Ammi visnaga), a plant indigenous to the Mediterranean region which has been used for centuries in Egypt as a spasmolytic.[2]

Visnadine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • (9R,10R)-10-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2R)-2-methylbutanoate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ECHA InfoCard100.006.833
Chemical and physical data
FormulaC21H24O7
Molar mass388.416 g·mol−1
3D model (JSmol)
SMILES
  • CC[C@H](C(=O)O[C@H]1[C@@](OC2=C([C@H]1OC(=O)C)C3=C(C=CC(=O)O3)C=C2)(C)C)C
InChI
  • InChI=1S/C21H24O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h7-11,18-19H,6H2,1-5H3/t11-,18-,19-/m1/s1
  • Key:GVBNSPFBYXGREE-CXWAGAITSA-N
  (verify)

References
  1. Durate J, Vallejo I, Pérez-Vizcaino F, Jiménez R, Zarzuelo A, Tamargo J (June 1997). "Effects of visnadine on rat isolated vascular smooth muscles". Planta Medica. Thieme Medical Publishers. 63 (3): 233–6. doi:10.1055/s-2006-957660. PMID 9225605.
  2. Smith E, Hosansky N, Bywater WG, van Tamelen EE (1957). "Constitution of Samidin, Dihydrosamidin and Visnadin". J. Am. Chem. Soc. 79 (13): 3534–3540. doi:10.1021/ja01570a062.
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