Table 1.5.a. Plasma methylmalonic acid: Total population
Geometric mean and selected percentiles of plasma concentrations (in µmol/L) for the total U.S. population aged3 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean and selected percentiles of plasma concentrations (in µmol/L) for Mexican Americans in the U.S.population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
5th
50th
95th
Males and Females
Total, 3 years and older
.111
(.108-.113)
.050
(.050-.060)
.110
(.100-.110)
.220
(.220-.240)
4726
3–5 years
.108
(.103-.112)
.070
(.060-.070)
.110
(.100-.110)
.180
(.170-.210)
271
6–11 years
.104
(.100-.109)
.060
(<LOD-.060)
.100
(.090-.100)
.180
(.160-.190)
656
12–19 years
.104
(.102-.107)
.060
(.050-.060)
.100
(.090-.100)
.190
(.180-.220)
1644
20–39 years
.108
(.103-.113)
.050
(<LOD-.060)
.100
(.090-.100)
.230
(.210-.270)
870
40–59 years
.116
(.112-.120)
.060
(.050-.060)
.110
(.100-.110)
.230
(.220-.270)
634
60 years and older
.150
(.145-.155)
.060
(.060-.080)
.130
(.120-.130)
.440
(.400-.530)
651
Males
Total, 3 years and older
.117
(.114-.121)
.060
(<LOD-.060)
.100
(.100-.110)
.250
(.230-.280)
2305
3–5 years
.108
(.102-.115)
.060†
(.050-.080)
.100
(.100-.110)
.180†
(.160-.210)
142
6–11 years
.104
(.099-.109)
.050
(<LOD-.070)
.110
(.100-.110)
.170
(.150-.200)
339
12–19 years
.111
(.107-.115)
.050
(<LOD-.060)
.110
(.100-.110)
.210
(.190-.230)
814
20–39 years
.118
(.112-.125)
.060
(<LOD-.060)
.110
(.100-.110)
.280
(.230-.390)
385
40–59 years
.125
(.119-.132)
.070
(.060-.070)
.110
(.110-.120)
.260
(.220-.350)
301
60 years and older
.151
(.141-.162)
.070
(.060-.080)
.140
(.130-.150)
.500
(.330-.630)
324
Females
Total, 3 years and older
.104
(.102-.106)
.050
(.050-.060)
.095
(.090-.100)
.210
(.190-.220)
2421
3–5 years
.107
(.100-.114)
.060†
(<LOD-.070)
.110
(.100-.120)
.170†
(.160-.210)
129
6–11 years
.105
(.100-.111)
.070
(.060-.070)
.100
(.090-.100)
.170
(.150-.200)
317
12–19 years
.097
(.095-.100)
.060
(.050-.060)
.100
(.090-.100)
.170
(.170-.200)
830
20–39 years
.097
(.093-.103)
< LOD
.100
(.090-.100)
.170
(.160-.210)
485
40–59 years
.107
(.102-.112)
.060
(.050-.060)
.090
(.090-.100)
.190
(.180-.220)
333
60 years and older
.148
(.140-.157)
.070
(<LOD-.080)
.120
(.120-.130)
.430
(.380-.560)
327
< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.
† Estimate is subject to greater uncertainty due to small cell size.
Geometric mean and selected percentiles of plasma concentrations (in µmol/L) for non-Hispanic blacks in the U.S.population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
5th
50th
95th
Males and Females
Total, 3 years and older
.110
(.107-.114)
.050
(.050-.060)
.100
(.100-.110)
.220
(.210-.240)
3768
3–5 years
.102
(.097-.107)
.060
(<LOD-.060)
.090
(.090-.100)
.170
(.160-.200)
245
6–11 years
.103
(.099-.107)
.070
(.060-.070)
.100
(.090-.100)
.170
(.150-.190)
619
12–19 years
.101
(.097-.105)
.050
(.050-.060)
.100
(.090-.100)
.180
(.180-.200)
1264
20–39 years
.101
(.097-.106)
.060
(.050-.060)
.100
(.090-.100)
.180
(.160-.220)
596
40–59 years
.115
(.109-.122)
.060
(<LOD-.060)
.110
(.100-.110)
.230
(.190-.270)
551
60 years and older
.156
(.148-.165)
.070
(.070-.080)
.140
(.130-.140)
.400
(.310-.500)
493
Males
Total, 3 years and older
.115
(.111-.119)
.050
(.050-.060)
.100
(.100-.110)
.230
(.220-.260)
1846
3–5 years
.103
(.096-.110)
.060†
(<LOD-.060)
.090
(.090-.110)
.180†
(.150-.230)
127
6–11 years
.104
(.100-.109)
.060
(<LOD-.060)
.100
(.090-.100)
.160
(.150-.190)
312
12–19 years
.107
(.102-.112)
.060
(<LOD-.060)
.100
(.090-.100)
.190
(.180-.240)
645
20–39 years
.110
(.103-.119)
.060
(<LOD-.070)
.100
(.100-.110)
.220
(.170-.260)
248
40–59 years
.119
(.111-.128)
< LOD
.120
(.110-.120)
.250
(.200-.290)
277
60 years and older
.155
(.143-.167)
.070
(.050-.070)
.140
(.120-.150)
.450
(.310-.560)
237
Females
Total, 3 years and older
.107
(.104-.110)
.050
(.050-.060)
.090
(.090-.100)
.220
(.200-.230)
1922
3–5 years
.101
(.094-.109)
.050†
(<LOD-.070)
.100
(.090-.100)
.150†
(.130-.190)
118
6–11 years
.102
(.097-.107)
.060
(.060-.070)
.100
(.090-.100)
.170
(.150-.200)
307
12–19 years
.095
(.090-.100)
< LOD
.080
(.080-.090)
.170
(.160-.180)
619
20–39 years
.095
(.092-.099)
.060
(.050-.060)
.080
(.080-.090)
.160
(.140-.180)
348
40–59 years
.112
(.104-.121)
.050
(<LOD-.070)
.110
(.100-.110)
.210
(.170-.230)
274
60 years and older
.157
(.147-.168)
.080
(.070-.080)
.140
(.120-.140)
.390
(.270-.620)
256
< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.
† Estimate is subject to greater uncertainty due to small cell size.
Geometric mean and selected percentiles of plasma concentrations (in µmol/L) for non-Hispanic whites in the U.S.population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
5th
50th
95th
Males and Females
Total, 3 years and older
.139
(.136-.142)
.080
(.070-.080)
.130
(.120-.130)
.290
(.280-.300)
6178
3–5 years
.129
(.123-.136)
.080
(.070-.080)
.120
(.110-.120)
.240
(.210-.270)
229
6–11 years
.130
(.124-.137)
.070
(.070-.080)
.130
(.110-.130)
.230
(.200-.270)
495
12–19 years
.124
(.120-.128)
.070
(.060-.070)
.110
(.110-.120)
.230
(.220-.280)
1073
20–39 years
.130
(.126-.133)
.070
(.060-.070)
.120
(.120-.130)
.250
(.230-.270)
1380
40–59 years
.136
(.132-.139)
.070
(.070-.080)
.130
(.120-.130)
.250
(.240-.280)
1285
60 years and older
.174
(.168-.179)
.090
(.080-.090)
.160
(.150-.160)
.450
(.380-.530)
1716
Males
Total, 3 years and older
.141
(.138-.145)
.080
(.070-.080)
.140
(.130-.140)
.280
(.270-.300)
3021
3–5 years
.136
(.127-.146)
.080†
(.050-.080)
.130
(.120-.140)
.250†
(.210-.340)
120
6–11 years
.134
(.126-.143)
.080
(.060-.080)
.120
(.110-.130)
.240
(.200-.310)
264
12–19 years
.129
(.124-.134)
.060
(.060-.070)
.110
(.110-.120)
.240
(.220-.280)
533
20–39 years
.132
(.127-.138)
.060
(.060-.070)
.130
(.120-.130)
.250
(.230-.290)
576
40–59 years
.139
(.134-.144)
.070
(.070-.080)
.120
(.120-.130)
.270
(.240-.300)
667
60 years and older
.174
(.168-.180)
.090
(.080-.100)
.170
(.160-.170)
.440
(.380-.490)
861
Females
Total, 3 years and older
.137
(.134-.140)
.080
(.070-.080)
.120
(.120-.130)
.290
(.280-.310)
3157
3–5 years
.122
(.113-.132)
.070†
(.070-.090)
.120
(.110-.120)
.200†
(.160-.250)
109
6–11 years
.125
(.117-.134)
.070
(.060-.080)
.110
(.110-.130)
.210
(.180-.270)
231
12–19 years
.119
(.114-.125)
.070
(.060-.070)
.100
(.100-.110)
.230
(.200-.300)
540
20–39 years
.127
(.123-.131)
.060
(.060-.070)
.110
(.110-.120)
.260
(.250-.280)
804
40–59 years
.132
(.128-.137)
.080
(.070-.080)
.130
(.120-.130)
.250
(.220-.300)
618
60 years and older
.173
(.166-.181)
.090
(.080-.090)
.160
(.150-.160)
.450
(.370-.570)
855
† Estimate is subject to greater uncertainty due to small cell size.