Table 5.4.a. Urinary O-desmethylangolensin: Total population

Geometric mean and selected percentiles of urine concentrations (in µg/L) for the total U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

4.18

(3.65-4.78)

< LOD

4.00

(3.40-4.74)

98.7

(75.9-122)

5065

6–11 years

5.97

(4.69-7.59)

< LOD

6.50

(4.63-9.68)

105

(59.6-176)

683

12–19 years

5.87

(4.59-7.50)

< LOD

6.47

(4.47-8.60)

122

(99.0-152)

1411

20–39 years

3.59

(2.91-4.43)

< LOD

3.03

(2.50-4.10)

121

(70.1-189)

1085

40–59 years

4.67

(3.64-5.98)

< LOD

4.30

(3.20-5.50)

111

(66.1-160)

896

60 years and older

2.94

(2.39-3.62)

< LOD

3.01

(1.90-4.12)

63.9

(40.3-73.7)

990

Males

Total, 6 years and older

4.24

(3.58-5.01)

< LOD

4.22

(3.50-5.29)

102

(74.2-137)

2462

6–11 years

6.61

(4.59-9.51)

< LOD

8.40

(3.96-11.3)

121

(52.7-235)

345

12–19 years

6.19

(4.51-8.50)

< LOD

7.00

(4.22-10.6)

105

(74.1-148)

690

20–39 years

3.44

(2.53-4.66)

< LOD

3.00

(2.00-4.47)

135

(53.9-259)

474

40–59 years

4.49

(3.45-5.86)

< LOD

4.50

(2.80-6.30)

108

(57.3-160)

455

60 years and older

3.18

(2.56-3.95)

< LOD

3.60

(2.43-5.57)

58.4

(36.3-85.2)

498

Females

Total, 6 years and older

4.12

(3.55-4.79)

< LOD

3.90

(3.00-4.56)

93.3

(70.9-128)

2603

6–11 years

5.38

(4.06-7.12)

< LOD

5.10

(3.43-8.80)

88.5

(59.2-161)

338

12–19 years

5.56

(4.09-7.55)

< LOD

5.69

(3.63-7.80)

137

(85.6-195)

721

20–39 years

3.75

(2.85-4.95)

< LOD

3.11

(2.40-4.90)

94.8

(57.2-228)

611

40–59 years

4.84

(3.43-6.82)

< LOD

4.10

(2.83-5.51)

125

(64.9-233)

441

60 years and older

2.77

(2.05-3.73)

< LOD

2.40

(1.50-4.00)

68.0

(33.8-81.6)

492

< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.

Table 5.4.b. Urinary O-desmethylangolensin: Mexican Americans

Geometric mean and selected percentiles of urine concentrations (in µg/L) for Mexican Americans in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

2.43

(1.78-3.34)

< LOD

1.80

(1.00-2.84)

86.0

(59.7-105)

1400

6–11 years

3.17

(2.23-4.49)

< LOD

2.84

(1.70-4.04)

61.5

(36.8-129)

212

12–19 years

3.07

(2.35-4.01)

< LOD

2.49

(1.83-3.50)

98.0

(65.2-137)

508

20–39 years

*

< LOD

1.40

(<LOD-3.40)

87.8

(44.2-129)

282

40–59 years

*

< LOD

1.30

(.700-3.60)

95.2

(36.5-191)

209

60 years and older

*

< LOD

.420

(<LOD-2.40)

25.2

(16.0-37.9)

189

Males

Total, 6 years and older

2.70

(1.77-4.13)

< LOD

2.10

(.800-4.70)

90.9

(66.4-129)

686

6–11 years

3.72

(2.29-6.02)

< LOD†

3.75

(1.60-8.50)

60.2†

(29.3-140)

111

12–19 years

3.32

(2.53-4.36)

< LOD

3.20

(2.00-5.02)

86.5

(61.0-144)

262

20–39 years

*

< LOD

1.31

(<LOD-6.54)

97.6

(59.7-189)

122

40–59 years

2.49

(1.48-4.19)

< LOD†

1.30

(.500-4.70)

122†

(28.3-237)

100

60 years and older

*

< LOD†

.420

(<LOD-3.30)

17.0†

(8.73-34.6)

91

Females

Total, 6 years and older

2.16

(1.63-2.87)

< LOD

1.62

(.880-2.50)

70.9

(40.6-90.1)

714

6–11 years

2.67

(1.88-3.81)

< LOD†

2.28

(1.44-3.30)

55.0†

(20.3-129)

101

12–19 years

2.80

(1.86-4.23)

< LOD

2.40

(1.25-3.60)

98.0

(48.2-152)

246

20–39 years

*

< LOD

1.39

(<LOD-2.83)

57.4

(25.2-88.3)

160

40–59 years

*

< LOD†

1.00

(<LOD-5.20)

86.0†

(18.6-191)

109

60 years and older

*

< LOD†

< LOD

33.2†

(18.4-150)

98

< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.

† Estimate is subject to greater uncertainty due to small cell size.

* Not calculated. Proportion of results below limit of detection was too high to provide a valid result.

Table 5.4.c. Urinary O-desmethylangolensin: Non-Hispanic blacks

Geometric mean and selected percentiles of urine concentrations (in µg/L) for non-Hispanic blacks in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

5.54

(4.63-6.64)

< LOD

6.40

(5.10-7.98)

116

(95.5-155)

1219

6–11 years

10.6

(7.78-14.5)

< LOD

13.4

(9.40-22.5)

226

(157-303)

235

12–19 years

10.5

(7.71-14.3)

< LOD

13.2

(8.40-17.8)

165

(131-238)

424

20–39 years

4.69

(2.93-7.51)

< LOD

5.55

(2.66-9.30)

103

(52.4-161)

187

40–59 years

4.42

(2.98-6.55)

< LOD

4.67

(2.40-8.71)

87.6

(58.0-114)

199

60 years and older

3.33

(1.97-5.64)

< LOD

3.04

(1.20-5.70)

99.1

(33.4-357)

174

Males

Total, 6 years and older

6.36

(4.70-8.59)

< LOD

7.20

(4.80-10.2)

143

(105-177)

590

6–11 years

13.2

(8.14-21.3)

< LOD

22.5

(10.1-39.1)

250

(158-355)

121

12–19 years

12.2

(8.73-17.0)

< LOD

14.5

(7.90-20.7)

171

(136-394)

194

20–39 years

5.91

(3.47-10.1)

< LOD†

5.93

(2.60-14.3)

128†

(52.4-308)

85

40–59 years

3.78

(2.07-6.90)

< LOD†

3.50

(1.10-9.30)

99.4†

(31.4-120)

103

60 years and older

4.09

(2.10-7.93)

< LOD†

5.30

(1.18-7.60)

77.4†

(33.7-255)

87

Females

Total, 6 years and older

4.94

(4.05-6.02)

< LOD

5.69

(4.50-7.90)

100

(73.8-128)

629

6–11 years

8.38

(5.30-13.2)

< LOD

10.4

(5.53-13.6)

147

(64.2-281)

114

12–19 years

9.07

(5.81-14.2)

< LOD

11.8

(6.64-20.1)

141

(95.1-201)

230

20–39 years

3.92

(2.22-6.93)

< LOD†

4.98

(1.40-9.40)

79.7†

(26.6-191)

102

40–59 years

5.04

(2.88-8.81)

< LOD†

5.30

(2.10-13.3)

81.6†

(40.2-313)

96

60 years and older

2.89

(1.62-5.16)

< LOD†

2.70

(.700-5.31)

99.1†

(21.0-502)

87

< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.

† Estimate is subject to greater uncertainty due to small cell size.

Table 5.4.d. Urinary O-desmethylangolensin: Non-Hispanic whites

Geometric mean and selected percentiles of urine concentrations (in µg/L) for non-Hispanic whites in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

4.25

(3.59-5.04)

< LOD

3.98

(3.30-4.80)

98.7

(72.8-135)

2021

6–11 years

5.98

(4.20-8.50)

< LOD

6.97

(3.43-11.5)

88.0

(45.0-191)

181

12–19 years

6.26

(4.47-8.77)

< LOD

6.50

(4.00-10.0)

122

(76.9-172)

360

20–39 years

3.47

(2.58-4.66)

< LOD

2.80

(2.03-4.40)

129

(61.0-228)

511

40–59 years

5.40

(4.03-7.23)

< LOD

4.56

(3.31-6.40)

137

(76.4-202)

405

60 years and older

2.88

(2.23-3.71)

< LOD

2.83

(1.71-4.20)

58.4

(30.2-78.0)

564

Males

Total, 6 years and older

4.22

(3.44-5.18)

< LOD

4.12

(3.31-5.40)

96.8

(65.7-137)

995

6–11 years

6.33

(3.52-11.4)

< LOD†

7.20

(3.30-15.7)

88.0†

(43.4-311)

90

12–19 years

6.27

(4.21-9.32)

< LOD

6.50

(3.60-13.5)

103

(61.6-148)

181

20–39 years

2.95

(1.95-4.48)

< LOD

2.51

(1.20-4.47)

96.0

(25.2-260)

223

40–59 years

5.35

(4.05-7.06)

< LOD

5.28

(3.31-8.00)

111

(58.4-178)

213

60 years and older

3.27

(2.60-4.12)

< LOD

3.60

(1.90-6.00)

58.4

(29.9-98.9)

288

Females

Total, 6 years and older

4.29

(3.50-5.25)

< LOD

3.98

(2.79-4.98)

106

(70.6-154)

1026

6–11 years

5.63

(3.55-8.95)

< LOD†

5.90

(2.70-14.3)

72.2†

(30.5-176)

91

12–19 years

6.26

(3.92-10.0)

< LOD

6.40

(3.50-11.7)

166

(58.3-367)

179

20–39 years

4.05

(2.76-5.94)

< LOD

3.80

(2.05-5.71)

135

(51.2-250)

288

40–59 years

5.46

(3.47-8.59)

< LOD

4.30

(2.36-6.40)

154

(64.9-322)

192

60 years and older

2.59

(1.81-3.72)

< LOD

2.10

(1.21-4.05)

59.9

(17.7-85.1)

276

< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.

† Estimate is subject to greater uncertainty due to small cell size.

Table 5.4.e. Urinary O-desmethylangolensin: Total population (creatinine corrected)

Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for the total U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

3.91

(3.38-4.52)

< LOD

3.74

(3.09-4.50)

87.6

(69.8-108)

5065

6–11 years

6.62

(5.15-8.52)

< LOD

6.64

(4.63-10.6)

93.7

(65.0-144)

683

12–19 years

4.28

(3.25-5.65)

< LOD

4.45

(3.22-6.51)

76.5

(61.6-102)

1411

20–39 years

2.89

(2.33-3.59)

< LOD

2.63

(1.96-3.66)

87.8

(50.8-126)

1085

40–59 years

4.67

(3.70-5.90)

< LOD

3.87

(2.73-5.68)

112

(71.8-155)

896

60 years and older

3.51

(2.81-4.37)

< LOD

3.19

(2.12-4.95)

64.7

(50.8-76.0)

990

Males

Total, 6 years and older

3.43

(2.85-4.12)

< LOD

3.51

(2.56-4.45)

75.2

(58.5-96.5)

2462

6–11 years

7.12

(4.73-10.7)

< LOD

6.80

(3.59-17.0)

97.8

(56.2-233)

345

12–19 years

4.45

(3.20-6.19)

< LOD

4.71

(3.41-8.02)

70.2

(48.8-115)

690

20–39 years

2.40

(1.73-3.33)

< LOD

2.05

(1.38-3.06)

88.9

(34.3-151)

474

40–59 years

3.76

(2.88-4.92)

< LOD

3.66

(2.46-5.76)

80.3

(53.1-118)

455

60 years and older

2.96

(2.35-3.73)

< LOD

2.92

(1.84-4.68)

51.7

(35.4-64.2)

498

Females

Total, 6 years and older

4.43

(3.76-5.21)

< LOD

3.92

(3.15-5.00)

98.3

(70.3-140)

2603

6–11 years

6.14

(4.67-8.09)

< LOD

6.61

(4.42-10.5)

88.0

(52.7-158)

338

12–19 years

4.12

(2.97-5.71)

< LOD

3.87

(2.50-5.90)

89.5

(61.4-111)

721

20–39 years

3.45

(2.58-4.61)

< LOD

3.62

(2.28-4.64)

86.0

(43.2-155)

611

40–59 years

5.76

(4.18-7.94)

< LOD

3.90

(2.69-7.27)

147

(85.2-280)

441

60 years and older

4.00

(2.93-5.47)

< LOD

3.40

(1.92-6.17)

69.8

(56.9-109)

492

< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.

Table 5.4.f. Urinary O-desmethylangolensin: Mexican Americans (creatinine corrected)

Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for Mexican Americans in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

2.26

(1.70-3.00)

< LOD

1.69

(1.12-2.67)

58.8

(48.6-87.8)

1400

6–11 years

4.11

(3.09-5.47)

< LOD

3.69

(2.16-7.00)

79.8

(53.6-114)

212

12–19 years

2.43

(1.85-3.19)

< LOD

2.13

(1.55-3.17)

61.5

(47.4-86.3)

508

20–39 years

*

< LOD

1.17

(<LOD-2.67)

56.4

(29.9-103)

282

40–59 years

*

< LOD

1.56

(.805-3.55)

58.8

(27.8-145)

209

60 years and older

*

< LOD

1.03

(<LOD-2.70)

30.4

(21.4-55.3)

189

Males

Total, 6 years and older

2.23

(1.52-3.27)

< LOD

1.64

(.932-3.90)

61.4

(48.6-93.0)

686

6–11 years

4.52

(2.88-7.09)

< LOD†

4.87

(1.72-8.95)

93.0†

(50.2-145)

111

12–19 years

2.50

(1.87-3.35)

< LOD

2.82

(1.54-4.31)

56.1

(37.2-71.2)

262

20–39 years

*

< LOD

1.45

(<LOD-4.56)

60.0

(25.8-113)

122

40–59 years

2.04

(1.26-3.32)

< LOD†

1.42

(.661-4.23)

57.2†

(19.6-218)

100

60 years and older

*

< LOD†

.698

(<LOD-3.02)

23.6†

(11.1-33.2)

91

Females

Total, 6 years and older

2.30

(1.77-2.99)

< LOD

1.69

(1.17-2.08)

57.7

(41.7-87.6)

714

6–11 years

3.73

(2.62-5.29)

< LOD†

2.44

(1.68-7.00)

78.3†

(27.1-108)

101

12–19 years

2.35

(1.57-3.52)

< LOD

1.78

(1.10-2.78)

68.3

(45.6-115)

246

20–39 years

*

< LOD

1.03

(<LOD-2.15)

41.7

(15.5-87.6)

160

40–59 years

*

< LOD†

1.77

(<LOD-3.90)

76.8†

(29.1-145)

109

60 years and older

*

< LOD†

< LOD

55.3†

(20.9-970)

98

< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.

† Estimate is subject to greater uncertainty due to small cell size.

* Not calculated. Proportion of results below limit of detection was too high to provide a valid result.

Table 5.4.g. Urinary O-desmethylangolensin: Non-Hispanic blacks (creatinine corrected)

Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for non-Hispanic blacks in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

3.73

(3.08-4.51)

< LOD

4.12

(3.20-5.48)

71.9

(54.7-100)

1219

6–11 years

9.94

(7.43-13.3)

< LOD

10.6

(8.27-18.2)

217

(118-305)

235

12–19 years

5.88

(4.34-7.98)

< LOD

7.25

(4.64-10.2)

95.0

(57.0-142)

424

20–39 years

2.68

(1.70-4.23)

< LOD

3.66

(1.67-5.69)

45.4

(26.8-100)

187

40–59 years

2.95

(2.07-4.19)

< LOD

2.93

(1.61-5.48)

60.4

(36.7-81.9)

199

60 years and older

3.11

(1.99-4.85)

< LOD

2.91

(1.64-4.83)

75.6

(47.2-167)

174

Males

Total, 6 years and older

3.84

(2.85-5.19)

< LOD

4.45

(2.64-7.30)

79.7

(55.2-118)

590

6–11 years

12.3

(7.52-20.0)

< LOD

18.0

(9.43-32.4)

233

(119-363)

121

12–19 years

6.63

(4.79-9.18)

< LOD

7.65

(4.69-11.1)

109

(59.1-198)

194

20–39 years

2.87

(1.70-4.84)

< LOD†

2.95

(1.28-8.61)

42.9†

(23.4-100)

85

40–59 years

2.27

(1.24-4.17)

< LOD†

2.18

(.996-5.61)

67.8†

(23.2-84.4)

103

60 years and older

3.05

(1.64-5.69)

< LOD†

2.79

(1.12-5.83)

79.7†

(26.3-151)

87

Females

Total, 6 years and older

3.63

(2.96-4.46)

< LOD

4.05

(3.26-5.22)

64.4

(47.0-90.4)

629

6–11 years

7.89

(5.57-11.2)

< LOD

8.27

(4.80-10.9)

104

(62.9-305)

114

12–19 years

5.24

(3.35-8.21)

< LOD

5.83

(3.15-11.1)

71.9

(47.5-142)

230

20–39 years

2.54

(1.45-4.46)

< LOD†

3.36

(1.42-5.69)

42.1†

(22.1-185)

102

40–59 years

3.67

(2.23-6.04)

< LOD†

3.61

(1.61-7.58)

54.4†

(34.1-147)

96

60 years and older

3.14

(1.90-5.19)

< LOD†

2.91

(1.31-6.30)

75.6†

(23.8-359)

87

< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.

† Estimate is subject to greater uncertainty due to small cell size.

Table 5.4.h. Urinary O-desmethylangolensin: Non-Hispanic whites (creatinine corrected)

Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for non-Hispanic whites in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

4.24

(3.55-5.07)

< LOD

3.78

(3.05-4.95)

97.4

(71.8-125)

2021

6–11 years

6.69

(4.67-9.58)

< LOD

6.80

(3.78-13.6)

85.2

(47.9-190)

181

12–19 years

4.79

(3.27-7.03)

< LOD

4.70

(3.14-8.91)

83.6

(60.3-125)

360

20–39 years

3.01

(2.28-3.98)

< LOD

2.72

(1.89-3.77)

97.4

(50.8-151)

511

40–59 years

5.67

(4.36-7.37)

< LOD

5.32

(2.96-7.96)

136

(71.8-210)

405

60 years and older

3.56

(2.74-4.64)

< LOD

3.17

(1.83-5.45)

64.5

(45.6-83.0)

564

Males

Total, 6 years and older

3.60

(2.89-4.49)

< LOD

3.51

(2.54-4.68)

76.4

(54.1-102)

995

6–11 years

7.20

(3.84-13.5)

< LOD†

6.80

(2.85-21.3)

90.2†

(39.0-407)

90

12–19 years

4.85

(3.15-7.46)

< LOD

4.71

(3.05-13.5)

62.2

(45.9-125)

181

20–39 years

2.24

(1.48-3.39)

< LOD

1.96

(1.27-3.06)

88.2

(23.5-151)

223

40–59 years

4.56

(3.50-5.94)

< LOD

4.91

(2.73-7.08)

96.5

(43.2-161)

213

60 years and older

3.12

(2.43-4.01)

< LOD

3.17

(1.83-5.10)

49.3

(31.6-76.0)

288

Females

Total, 6 years and older

4.97

(4.04-6.10)

< LOD

4.15

(3.15-6.03)

120

(72.2-153)

1026

6–11 years

6.19

(4.04-9.49)

< LOD†

6.86

(3.85-13.6)

84.7†

(37.9-179)

91

12–19 years

4.74

(2.93-7.67)

< LOD

4.64

(2.43-8.27)

98.9

(61.4-292)

179

20–39 years

4.01

(2.77-5.79)

< LOD

4.01

(2.52-5.73)

97.4

(45.6-165)

288

40–59 years

7.07

(4.69-10.7)

< LOD

5.35

(2.45-10.1)

159

(97.6-421)

192

60 years and older

3.96

(2.70-5.81)

< LOD

2.86

(1.64-6.60)

71.5

(49.1-114)

276

< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.

† Estimate is subject to greater uncertainty due to small cell size.