Valsartan/hydrochlorothiazide

Valsartan/hydrochlorothiazide
Combination of
ValsartanAngiotensin II receptor antagonist
HydrochlorothiazideThiazide diuretic
Names
Trade namesCo-vasotec, Diovan HCT, Co-Diovan, others
Clinical data
WHO AWaReUnlinkedWikibase error: ⧼unlinkedwikibase-error-statements-entity-not-set⧽
Pregnancy
category
  • US: D (Evidence of risk)
    Routes of
    use
    By mouth
    Defined daily dosenot established[1]
    External links
    AHFS/Drugs.comFDA Professional Drug Information
    MedlinePlusa611032
    Legal
    License data
    Legal status

    Valsartan/hydrochlorothiazide, sold under the trade name Co-Diovan among others, is an medication used to treat high blood pressure when valsartan is not sufficient.[2] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic.[3] It is taken by mouth.[3]

    Common side effects include dizziness and headaches.[3] Serious side effects may include allergic reactions, electrolyte abnormalities, and glaucoma.[4] Use in pregnancy is not recommended.[4]

    The combination was approved for medical use in the United States in 1998.[3] It is available as a generic medication.[2] A month supply in the United Kingdom costs the NHS about 1.85 as of 2019.[2] In the United States the wholesale cost of this amount is about US$4.40.[5] In 2017, it was the 133rd most commonly prescribed medication in the United States, with more than five million prescriptions.[6][7]

    Dosage

    The defined daily dose is not established[1]

    Society and culture

    Cost

    A month supply in the United Kingdom costs the NHS about 1.85 as of 2019.[2] In the United States the wholesale cost of this amount is about US$4.40.[5] In 2017, it was the 133rd most commonly prescribed medication in the United States, with more than five million prescriptions.[7][6]

    References

    1. 1 2 "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 1 July 2021. Retrieved 10 September 2020.
    2. 1 2 3 4 British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 179. ISBN 9780857113382.
    3. 1 2 3 4 "Hydrochlorothiazide and valsartan Uses, Side Effects & Warnings". Drugs.com. Archived from the original on 8 February 2018. Retrieved 10 March 2019.
    4. 1 2 "Valsartan and Hydrochlorothiazide - FDA prescribing information, side effects and uses". Drugs.com. Archived from the original on 16 July 2017. Retrieved 10 March 2019.
    5. 1 2 "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services. Archived from the original on 2019-03-06. Retrieved 3 March 2019.
    6. 1 2 "The Top 300 of 2020". ClinCalc. Archived from the original on 18 March 2020. Retrieved 11 April 2020.
    7. 1 2 "Hydrochlorothiazide; Valsartan - Drug Usage Statistics". ClinCalc. Archived from the original on 11 April 2020. Retrieved 11 April 2020.
    Identifiers:



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