Adhyperforin
Adhyperforin is a phytochemical found in the members of the plant genus Hypericum including St. John's Wort.[1] It has a very similar pharmacological profile to hyperforin and acts as a TRPC6 ion channel activator,[1] thereby inhibiting the reuptake of various neurotransmitters including serotonin, norepinephrine, dopamine, GABA, and glutamate.[1] Adhyperforin is found in St. John's Wort in levels approximately 1/10 those of hyperforin.[1]
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Routes of administration | Oral |
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Formula | C36H54O4 |
Molar mass | 550.824 g·mol−1 |
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See also
References
- Jensen AG, Hansen SH, Nielsen EO (2001). "Adhyperforin as a contributor to the effect of Hypericum perforatum L. in biochemical models of antidepressant activity". Life Sci. 68 (14): 1593–1605. doi:10.1016/S0024-3205(01)00946-8. PMID 11263672.
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