Almestrone

Almestrone (INNTooltip International Nonproprietary Name) (developmental code names Ba 38372, Ciba 38372), also known as 7α-methylestrone, is a synthetic, steroidal estrogen which was synthesized in 1967 but was never marketed.[1] It is used as a precursor in the synthesis of several highly active steroids.[2][3]

Almestrone
Clinical data
Other namesBa 38372; Ciba 38372; 7α-Methylestrone
Routes of
administration		By mouth
Drug classEstrogen
ATC code
  • None
Identifiers
  • (7R,8R,9S,13S,14S)-3-hydroxy-7,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard100.212.018
Chemical and physical data
FormulaC19H24O2
Molar mass284.399 g·mol−1
3D model (JSmol)
  • CC1CC2=C(C=CC(=C2)O)C3C1C4CCC(=O)C4(CC3)C
  • InChI=InChI=1S/C19H24O2/c1-11-9-12-10-13(20)3-4-14(12)15-7-8-19(2)16(18(11)15)5-6-17(19)21/h3-4,10-11,15-16,18,20H,5-9H2,1-2H3/t11-,15-,16+,18-,19+/m1/s1
  • Key:JUAJXSMWFOFDFC-MNHDCVOLSA-N

See also

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 900–. ISBN 978-1-4757-2085-3.
  2. Krause N, Aksin-Artok Ö (2011). "Copper-Mediated and Copper-Catalyzed Addition and Substitution Reactions of Extended Multiple Bond Systems". PATai's Chemistry of Functional Groups. doi:10.1002/9780470682531.pat0450. ISBN 9780470682531.
  3. Morais GR, Yoshioka N, Watanabe M, Mataka S, Oliveira CD, Thiemann T (2006). "C7-Substituted Estranes and Related Steroids". Mini-Reviews in Organic Chemistry. 3 (3): 229–251. doi:10.2174/1570193X10603030229. ISSN 1570-193X.
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