Estrapronicate

Estrapronicate (INNTooltip International Nonproprietary Name), also known as estradiol nicotinate propionate is an estrogen medication and estrogen ester which was never marketed.[1] It was studied as a component of the experimental tristeroid combination drug Trophobolene, which contained nandrolone decanoate, estrapronicate, and hydroxyprogesterone heptanoate.[2][3]

Estrapronicate
Clinical data
Other namesEstradiol propionicotinate; Estradiol propionate nicotinate; Estradiol nicotinate propionate; Estradiol 17β-nicotinate 3-propionate
Routes of
administration		Intramuscular injection
Drug classEstrogen; Estrogen ester
Identifiers
  • [(8R,9S,13S,14S,17S)-13-Methyl-3-propanoyloxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] pyridine-3-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.021.786
Chemical and physical data
FormulaC27H31NO4
Molar mass433.548 g·mol−1
3D model (JSmol)
  • CCC(=O)OC1=CC2=C(C=C1)C3CCC4(C(C3CC2)CCC4OC(=O)C5=CN=CC=C5)C
  • InChI=1S/C27H31NO4/c1-3-25(29)31-19-7-9-20-17(15-19)6-8-22-21(20)12-13-27(2)23(22)10-11-24(27)32-26(30)18-5-4-14-28-16-18/h4-5,7,9,14-16,21-24H,3,6,8,10-13H2,1-2H3/t21-,22-,23+,24+,27+/m1/s1
  • Key:FXMSQUVSUXBBAB-TXDQRGGKSA-N

See also

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 898–. ISBN 978-1-4757-2085-3.
  2. Excerpta medica. Section 8, Neurology and neurosurgery. 1981. p. 10.
  3. Testosterone Congeners—Advances in Research and Application: 2013 Edition: ScholarlyBrief. ScholarlyEditions. 21 June 2013. pp. 137–. ISBN 978-1-4816-9288-5.



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