Glafenine

Glafenine is a nonsteroidal anti-inflammatory drug (NSAID). Use of glafenine is limited due to the risk of anaphylaxis and acute kidney failure.[1][2]

Glafenine
Clinical data
ATC code
Identifiers
  • 2,3-Dihydroxypropyl 2-[(7-chloro-4-quinolinyl)amino]benzoate
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.021.197
Chemical and physical data
FormulaC19H17ClN2O4
Molar mass372.81 g·mol−1
3D model (JSmol)
Melting point169 to 170 °C (336 to 338 °F)
  • O=C(OCC(O)CO)c1ccccc1Nc2c3ccc(Cl)cc3ncc2
  • InChI=1S/C19H17ClN2O4/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23/h1-9,13,23-24H,10-11H2,(H,21,22)
  • Key:GWOFUCIGLDBNKM-UHFFFAOYSA-N

See also

References
  1. "Withdrawal of glafenine". The Lancet. 339 (8789): 357. 1992. doi:10.1016/0140-6736(92)91670-4. S2CID 54255503.
  2. Kleinknecht D, Landais P, Goldfarb B (June 1986). "Analgesic and non-steroidal anti-inflammatory drug-associated acute renal failure: a prospective collaborative study". Clinical Nephrology. 25 (6): 275–81. PMID 2873910.
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