NCAPG

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene.[5][6][7] CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.

NCAPG
Identifiers
AliasesNCAPG, CAPG, CHCG, NY-MEL-3, YCG1, non-SMC condensin I complex subunit G
External IDsOMIM: 606280 MGI: 1930197 HomoloGene: 44071 GeneCards: NCAPG
Orthologs
SpeciesHumanMouse
Entrez

64151

54392

Ensembl

ENSG00000109805

ENSMUSG00000015880

UniProt

Q9BPX3

E9PWG6

RefSeq (mRNA)

NM_022346

NM_019438

RefSeq (protein)

NP_071741

NP_062311

Location (UCSC)Chr 4: 17.81 – 17.84 MbChr 5: 45.83 – 45.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

NCAPG has been shown to interact with DNMT3B.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000109805 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000015880 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Jäger D, Stockert E, Jäger E, Güre AO, Scanlan MJ, Knuth A, Old LJ, Chen YT (Aug 2000). "Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library". Cancer Res. 60 (13): 3584–91. PMID 10910072.
  6. Kimura K, Cuvier O, Hirano T (Feb 2001). "Chromosome condensation by a human condensin complex in Xenopus egg extracts". J. Biol. Chem. 276 (8): 5417–20. doi:10.1074/jbc.C000873200. PMID 11136719.
  7. "Entrez Gene: NCAPG non-SMC condensin I complex, subunit G".
  8. Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Res. 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596. PMID 15148359.

Further reading


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