Nuclear protein

A nuclear protein is a protein found in the cell nucleus.[1] Proteins are transported inside the nucleus with the help of the nuclear pore complex, which acts a barrier between cytoplasm and nuclear membrane. The import and export of proteins through the nuclear pore complex plays a fundamental role in gene regulation and other biological functions.[2][3]

Diagram of nuclear uptake of proteins

References
  1. "MeSH Browser". meshb.nlm.nih.gov. Retrieved 2019-05-12.
  2. Freitas N, Cunha C (December 2009). "Mechanisms and signals for the nuclear import of proteins". Current Genomics. 10 (8): 550–7. doi:10.2174/138920209789503941. PMC 2817886. PMID 20514217.
  3. Jühlen R, Fahrenkrog B (December 2018). "Moonlighting nuclear pore proteins: tissue-specific nucleoporin function in health and disease". Histochemistry and Cell Biology. 150 (6): 593–605. doi:10.1007/s00418-018-1748-8. PMID 30361777.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.