Nexeridine
Nexeridine[1] (INN), or as nexeridine hydrochloride (USAN) (code name Compound 673-082), is an opioid analgesic with a similar structure to those of pethidine and tramadol.[2][3][4] It was synthesized and assayed in 1975 but was never marketed.[2] The active isomer is (1R,2S)-1-[(2R)-1-(Dimethylamino)-2-propanyl]-2-phenylcyclohexyl acetate hydrochloride (1:1).[5]
Not to be confused with Meperidine.
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Formula | C19H29NO2 |
Molar mass | 303.446 g·mol−1 |
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References
- US 3974157, "1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters"
- Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1417–. ISBN 978-0-412-46630-4.
- Kar A (1 January 2005). Medicinal Chemistry. New Age International. pp. 268–269. ISBN 978-81-224-1565-0.
- Unlisted Drugs, Volumes 27-28. Pharmaceutical Section, Special Libraries Association. 1975.
- "(1R,2S)-1-[(2R)-1-(Dimethylamino)-2-propanyl]-2-phenylcyclohexyl acetate hydrochloride (1:1)". ChemSpider.
MORTooltip μ-opioid receptor |
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DORTooltip δ-opioid receptor |
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KORTooltip κ-opioid receptor |
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NOPTooltip Nociceptin receptor |
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Unsorted |
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