Panuramine

Panuramine
Clinical data
ATC code	None;
Identifiers
	IUPAC name N-{[1-(naphthalen-2-ylmethyl)piperidin-4-yl]carbamoyl}benzamide;
CAS Number	80349-58-2 ; 80349-03-7 (HCl);
PubChem CID	72002;
ChemSpider	65002;
UNII	1UWS3T8EAB;
CompTox Dashboard (EPA)	DTXSID30230257 ;
Chemical and physical data
Formula	C24H25N3O2
Molar mass	387.483 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(c1ccccc1)NC(=O)NC4CCN(Cc2ccc3c(c2)cccc3)CC4;

Panuramine (Wy-26,002) is an antidepressant which was synthesized in 1981 by Wyeth.[1] It acts as a potent and selective serotonin reuptake inhibitor (SSRI).[2] It was never marketed.[1]

References

David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9.
Blurton PA, Broadhurst AM, Cross JA, Ennis C, Wood MD, Wyllie MG (September 1984). "Panuramine, a selective inhibitor of uptake of 5-hydroxytryptamine in the brain of the rat". Neuropharmacology. 23 (9): 1049–52. doi:10.1016/0028-3908(84)90127-8. PMID 6514142. S2CID 27269043.

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