Dupracetam

Dupracetam is a nootropic drug from the racetam family.[1][2]

Dupracetam
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: unscheduled
Identifiers
IUPAC name
  • 2-(2-oxopyrrolidin-1-yl)-N'-[2-(2-oxopyrrolidin-1-yl)acetyl]acetohydrazide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.056.279
Chemical and physical data
FormulaC12H18N4O4
Molar mass282.300 g·mol−1
3D model (JSmol)
SMILES
  • C1CC(=O)N(C1)CC(=O)NNC(=O)CN2CCCC2=O
InChI
  • InChI=1S/C12H18N4O4/c17-9(7-15-5-1-3-11(15)19)13-14-10(18)8-16-6-2-4-12(16)20/h1-8H2,(H,13,17)(H,14,18) N
  • Key:YPUPYVWSTBYCBY-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

One of its metabolites, 1-Methylhydantoin, displays renal toxicity in high doses.[3]

See also

References

  1. Dell HD, Jacobi H, Kamp R, Kurz J, Wünsche C (August 1981). "[1-Methylhydantoin, an unexpected metabolite of the intelligence-affecting substance dupracetam (author's transl)]". Archiv der Pharmazie (in German). 314 (8): 697–702. doi:10.1002/ardp.19813140808. PMID 7294979. S2CID 95603731.
  2. Hall ED, Von Voigtlander PF (November 1987). "Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission". Neuropharmacology. 26 (11): 1573–9. doi:10.1016/0028-3908(87)90003-7. PMID 2829047. S2CID 7759558.
  3. Yang, B.; Liu, D.; Li, C.; Liu, F.; Peng, Y.; Jiang, Y. (2007). "1-Methylhydantoin Cytotoxicity on Renal Proximal Tubular Cells in Vitro". Renal Failure. 29 (8): 1025–1029. doi:10.1080/08860220701641272. PMID 18067051. S2CID 26843776.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.