Phenylpiracetam hydrazide

Phenylpiracetam hydrazide, also known as fonturacetam hydrazide,[1] is a racetam that is a derivative of phenylpiracetam in which the amide group is replaced with a hydrazide group. It was first reported by a Russian research group in 1980 as part of a series of chemical compounds investigated as anticonvulsants.[2] In an electroshock test it was found to have an ED50 of 310 mg/kg.[2]

Phenylpiracetam hydrazide
Clinical data
Trade namesPhenylpiracetam hydrazide
Other namesFonturacetam hydrazide
Pregnancy
category
  • Unknown
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • US: Not FDA approved; unscheduled
Identifiers
IUPAC name
  • 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetohydrazide
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC12H15N3O2
Molar mass233.271 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
SMILES
  • c1ccc(cc1)C2CC(=O)N(C2)CC(=O)NN
InChI
  • InChI=1S/C12H15N3O2/c13-14-11(16)8-15-7-10(6-12(15)17)9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,14,16) Y
  • Key:AXQUMNYYLGUJIZ-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

Sale on the internet

All piracetam derivatives are not permitted to be sold as dietary supplements in the United States.[3] However, because they lack scheduling, piracetam derivatives like phenylpiracetam hydrazide are sold over the clear net accompanied by indications of not being for human consumption.

See also

References
  1. "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 63" (PDF). WHO Drug Information. 24 (1): 56. 2010. Archived from the original (PDF) on May 21, 2014. Retrieved 26 November 2015.
  2. Glozman OM, Morozov IS, Zhmurenko LA, Zagorevskii VA (1980). "Synthesis and anticonvulsive activity of 4-phenyl-2-pyrrolidinone-1-acetic acid amides". Khimiko-Farmatsevticheskii Zhurnal (in Russian). 14 (11): 43–48.
  3. jamanetwork.com https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2755291#:~:text=The%20FDA%20has%20determined%20that,supplements%20remain%20available%20for%20sale. Retrieved 2022-09-13. {{cite web}}: Missing or empty |title= (help)


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