Rolziracetam

Rolziracetam is a nootropic drug of the racetam family.

Rolziracetam
Clinical data
Other names2,6,7,8-tetrahydro-1H-pyrrolizine-3,5-dione
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • AU: S4 (Prescription only)
  • US: Unscheduled
Identifiers
IUPAC name
  • dihydro-1H-pyrrolizine-3,5(2H,6H)-dione
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC7H9N2O2
Molar mass153.161 g·mol−1
3D model (JSmol)
SMILES
  • O=C2N1C(=O)CCC1CC2
InChI
  • InChI=1S/C7H9NO2/c9-6-3-1-5-2-4-7(10)8(5)6/h5H,1-4H2 Y
  • Key:IEZDOKQWPWZVQF-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

Rolziracetam was found to improve performance on a delayed-response task in aged rhesus monkeys. It has a wide margin of safety in animals and has been evaluated for use in cognitively impaired human subjects.[1]

See also

References

  1. Butler DE, Leonard JD, Caprathe BW, L'Italien YJ, Pavia MR, Hershenson FM, Poschel PH, Marriott JG (March 1987). "Amnesia-reversal activity of a series of cyclic imides". Journal of Medicinal Chemistry. 30 (3): 498–503. doi:10.1021/jm00386a010. PMID 3820221.


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