Esuprone

Esuprone is an experimental drug candidate being investigated as an antidepressant.[2] It acts as a monoamine oxidase A (MAO-A) inhibitor.[3]

Esuprone
Names
Preferred IUPAC name
3,4-Dimethyl-2-oxo-2H-1-benzopyran-7-yl ethanesulfonate
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
UNII
InChI
  • InChI=1S/C13H14O5S/c1-4-19(15,16)18-10-5-6-11-8(2)9(3)13(14)17-12(11)7-10/h5-7H,4H2,1-3H3 Y
    Key: CHDGAVDQRSPBTA-UHFFFAOYSA-N Y
  • InChI=1/C13H14O5S/c1-4-19(15,16)18-10-5-6-11-8(2)9(3)13(14)17-12(11)7-10/h5-7H,4H2,1-3H3
    Key: CHDGAVDQRSPBTA-UHFFFAOYAR
SMILES
  • O=S(=O)(Oc2ccc\1c(OC(=O)/C(=C/1C)C)c2)CC
Properties[1]
Chemical formula
 C13H14O5S
Molar mass 282.31 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

References
  1. Ganellin, C. R (1996). Dictionary of pharmacological agents. CRC Press. p. 1056. ISBN 978-0-412-46630-4.
  2. Vértes, Attila (2003). Handbook of nuclear chemistry. Springer. p. 155. ISBN 978-1-4020-1316-4.
  3. Bergström, M; Westerberg, G; Németh, G; Traut, M; Gross, G; Greger, G; Müller-Peltzer, H; Safer, A; et al. (1997). "MAO-A inhibition in brain after dosing with esuprone, moclobemide and placebo in healthy volunteers: In vivo studies with positron emission tomography". European Journal of Clinical Pharmacology. 52 (2): 121–8. doi:10.1007/s002280050260. PMID 9174681. S2CID 25359613.
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