Naples phlebovirus

Naples phlebovirus is an antigenic species of genus Phlebovirus within the family Phenuiviridae of the order Bunyavirales. It is an enveloped RNA virus with a tripartite genome e Uukuniemi (UUK) serogroup. The Sandfly group's natural reservoir are sandflies, while the natural reservoir for Uukuniemi is ticks. The SFNV serogroup consists of two main serocomplexes associated with disease in humans, the Naples and Sicilian serocomplexes. Sandfly fever induces myalgia, fever, and elevated liver enzymes in humans. It is difficult to diagnose outside endemic areas.[1][2]

Naples phlebovirus
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Phenuiviridae
Genus: Phlebovirus
Species:
Naples phlebovirus
Synonyms
  • Sandfly fever Naples phlebovirus

Natural reservoir

Phlebotomine sandflies (Psychodidae) are the natural reservoir and transmit to humans via bite. Psychodidae has a wide geographical distribution.[3][4][5][6]

References

  1. Nichol ST, Beaty BJ, Elliott RM, Goldbach R, Plyusnin A (2005). "The Negative Stranded ssRNA Viruses: Genus Phlebovirus". In Faguet CM, Mayo MA, Maniloff J, Desselberger U, Ball LA (eds.). Virus Taxonomy: Eighth Report of the International Committee on Taxonomy of Viruses. Elsevier. pp. 709–711. ISBN 9780080575483.
  2. Palacios G, Savji N, Travassos da Rosa A, Desai A, Sanchez-Seco MP, Guzman H, Lipkin WI, Tesh R (2013). "Characterization of the Salehabad virus species complex of the genus Phlebovirus (Bunyaviridae)". J Gen Virol. 94 (Pt 4): 837–842. doi:10.1099/vir.0.048850-0. PMC 3709685. PMID 23239568.
  3. Mertz GJ (1997). "Bunyaviridae: Bunyaviruses, Phleboviruses, Nairoviruses and Hantaviruses". In Richman DD, Whitley RJ, Hayden FG (eds.). Clinical Virology. Churchill-Livingstone. ISBN 9780443076534.
  4. Guler S, Guler E, Caglayik DY, Kokoglu OF, Ucmak H, Bayrakdar F, Uyar Y (2012). "A sandfly fever virus outbreak in the East Mediterranean region of Turkey". Int J Infect Dis. 16 (4): e244–6. doi:10.1016/j.ijid.2011.12.001. PMID 22293495.
  5. Schultze D, Korte W, Rafeiner P, Niedrig M (2012). "First report of sandfly fever virus infection imported from Malta into Switzerland, October 2011". Euro Surveill. 17 (27): 20209. doi:10.2807/ese.17.27.20209-en. PMID 22790604.
  6. Nissen NB, Jespersen S, Vinner L, Fomsgaard A, Laursen A (2011). "Sandfluevirusmeningitis hos en dansk turist efter ophold i Toscana" [Sandfly virus meningitis in a Danish traveller returning from Tuscany]. Ugeskr Laeger (in Danish). 173 (40): 2505–6. PMID 21975188.
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