Onchidal

Onchidal
Clinical data
ATC code	none;
Identifiers
	IUPAC name (1E,3E)-5-(2,2-Dimethyl-6-methylenecyclohexyl)-3-formylpenta-1,3-dien-1-yl acetate;
CAS Number	67656-42-2;
PubChem CID	6441116;
ChemSpider	4945331 ;
CompTox Dashboard (EPA)	DTXSID90897204 ;
Chemical and physical data
Formula	C17H24O3
Molar mass	276.376 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)O\C=C\C(=C/CC1C(=C)CCCC1(C)C)\C=O;
	InChI InChI=1S/C17H24O3/c1-13-6-5-10-17(3,4)16(13)8-7-15(12-18)9-11-20-14(2)19/h7,9,11-12,16H,1,5-6,8,10H2,2-4H3/b11-9+,15-7+ ; Key:BEKQPDFPPJFVJP-AHSQCEKMSA-N ;
	(verify)

Onchidal is a naturally occurring neurotoxin produced as a defensive secretion by the mollusc Onchidella binneyi and several other related species in Onchidella, a genus of small, air-breathing sea slugs. It acts as an irreversible acetylcholinesterase inhibitor, the same mechanism of action as that of the deadly nerve agents, however onchidal is not an organophosphorus or carbamate compound and bears little resemblance to other compounds of this nature.^[1]

References

↑ Abramson SN, Radic Z, Manker D, Faulkner DJ, Taylor P (September 1989). "Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action". Molecular Pharmacology. 36 (3): 349–54. PMID 2779521.

This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[pmid2779521-1] Abramson SN, Radic Z, Manker D, Faulkner DJ, Taylor P (September 1989). "Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action". Molecular Pharmacology. 36 (3): 349–54. PMID 2779521.

[1]