3',4'-Dimethoxy-α-pyrrolidinopentiophenone

3',4'-Dimethoxy-α-pyrrolidinopentiophenone (also known as O-2512, 3,4-dimethoxy-α-PVP, 3,4-DMPV, DMPVP) is a synthetic stimulant drug of the cathinone class that has been sold online as a designer drug.[1][2] It is a relatively weak inhibitor of serotonin reuptake and has little affinity in vitro for dopamine or noradrenaline transporters.[3]

3',4'-Dimethoxy-α-pyrrolidinopentiophenone
Legal status
Legal status
Identifiers
  • 1-(3,4-Dimethoxyphenyl)-2-(1-pyrrolidinyl)-1-pentanone
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC17H26NO3
Molar mass292.399 g·mol−1
3D model (JSmol)
  • COC=1C=C(C=CC1OC)C(C(CCC)N1CCCC1)=O
  • InChI=1/C17H25NO3/c1-4-7-14(18-10-5-6-11-18)17(19)13-8-9-15(20-2)16(12-13)21-3/h8-9,12,14H,4-7,10-11H2,1-3H3
  • Key:AGRVUDWDZKZCAA-UHFFFAOYSA-N

See also

References
  1. "3,4-dimethoxy-α-Pyrrolidinopentiophenone". Cayman Chemical. Retrieved 11 August 2015.
  2. Uchiyama N, Matsuda S, Kawamura M, Shimokawa Y, Kikura-Hanajiri R, Aritake K, et al. (October 2014). "Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products". Forensic Science International. 243: 1–13. doi:10.1016/j.forsciint.2014.03.013. PMID 24769262.
  3. Meltzer PC, Butler D, Deschamps JR, Madras BK (February 2006). "1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors". Journal of Medicinal Chemistry. 49 (4): 1420–1432. doi:10.1021/jm050797a. PMC 2602954. PMID 16480278.
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