Crotylbarbital

Crotylbarbital (Mepertan, Kalipnon, Barotal), also known as crotarbital, is a barbiturate derivative developed by Eli Lilly in the 1930s.[1] It has sedative and hypnotic effects,[2] and was used for the treatment of insomnia until it was replaced by newer alternative drugs with fewer side effects and lower risk of overdose.

Crotylbarbital
Clinical data
ATC code
  • none
Identifiers
  • 5-but-2-enyl-5-ethyl-1,3-diazinane-2,4,6-trione
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.016.162
Chemical and physical data
FormulaC10H14N2O3
Molar mass210.233 g·mol−1
3D model (JSmol)
  • O=C1NC(=O)NC(=O)C1(CC)C/C=C/C
  • InChI=1S/C10H14N2O3/c1-3-5-6-10(4-2)7(13)11-9(15)12-8(10)14/h3,5H,4,6H2,1-2H3,(H2,11,12,13,14,15)/b5-3+ checkY
  • Key:KNMOHCLEINXVBG-HWKANZROSA-N checkY
  (verify)

See also

References
  1. US 2250422, Shonle HA, Doran WJ, "Alkyl-crotyl barbituric acids and their salts", issued 22 July 1941, assigned to Eli Lilly
  2. Walther T, Meyer FP, Puchta K, Walther H (June 1983). "Effect of an acute dose of crotylbarbital on reaction time and attention testing in healthy human subjects". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 21 (6): 306–10. PMID 6136469.


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