Heptabarb

Heptabarb (INN; Eudan, Medapan, Medomin, Noctyn), also known as heptabarbitone (BAN) or heptabarbital, is a sedative and hypnotic drug of the barbiturate family.[2][3] It was used in Europe for the treatment of insomnia from the 1950s onwards, but has since been discontinued.[2][3]

Heptabarb
Clinical data
Other namesG-475
Routes of
administration		Oral[1]
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability83%[1]
MetabolismHepatic
Elimination half-life6.1-11.2 hours[1]
ExcretionRenal[1]
Identifiers
  • 5-cyclohept-1-en-1-yl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.371
Chemical and physical data
FormulaC13H18N2O3
Molar mass250.298 g·mol−1
3D model (JSmol)
  • O=C1NC(=O)NC(=O)C1(/C2=C/CCCCC2)CC
  • InChI=1S/C13H18N2O3/c1-2-13(9-7-5-3-4-6-8-9)10(16)14-12(18)15-11(13)17/h7H,2-6,8H2,1H3,(H2,14,15,16,17,18) checkY
  • Key:PAZQYDJGLKSCSI-UHFFFAOYSA-N checkY
  (verify)

See also

References
  1. Breimer DD, de Boer AG (December 1975). "Pharmacokinetics and relative bioavailability of heptabarbital and heptabarbital sodium after oral administration to man". European Journal of Clinical Pharmacology. 9 (2–3): 169–78. doi:10.1007/bf00614014. PMID 9299. S2CID 32380531.
  2. Ganellin CR, Triggle DJ, Macdonald F (1997). Dictionary of pharmacological agents. CRC Press. p. 1003. ISBN 978-0-412-46630-4. Retrieved 26 November 2011.
  3. Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 513. ISBN 978-3-88763-075-1. Retrieved 26 November 2011.


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