Fluoroethyl-L-tyrosine (18F)

Fluoroethyl-l-tyrosine (18F) or 18F-FET is a neuro-oncologic PET tracer.[2]

Fluoroethyl-L-tyrosine (18F)
Clinical data
Other names18F-FET; O-(2-(18F)fluoroethyl)-l-tyrosine, O-(2-Fluorethyl)-l-thyrosine, l-(18F)FET[1]
Routes of
administration		Intravenous
ATC code
Identifiers
IUPAC name
  • (2S)-2-Amino-3-[4-(2-fluoroethoxy)phenyl]propanoic acid
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC11H14FNO3
Molar mass227.235 g·mol−1
3D model (JSmol)
SMILES
  • C1=CC(=CC=C1C[C@@H](C(=O)O)N)OCC[18F]
InChI
  • InChI=1S/C11H14FNO3/c12-5-6-16-9-3-1-8(2-4-9)7-10(13)11(14)15/h1-4,10H,5-7,13H2,(H,14,15)/t10-/m0/s1/i12-1
  • Key:QZZYPHBVOQMBAT-LRAGLOQXSA-N

See also
  • Fluoroethyl

References
  1. CID 54255856 from PubChem
  2. Galldiks N, Stoffels G, Filss C, Rapp M, Blau T, Tscherpel C, et al. (September 2015). "The use of dynamic O-(2-18F-fluoroethyl)-l-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma". Neuro-Oncology. 17 (9): 1293–300. doi:10.1093/neuonc/nov088. PMC 4588758. PMID 26008606.
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