Technetium (99mTc) tilmanocept

Technetium (99mTc) tilmanocept, trade name Lymphoseek, is a radiopharmaceutical diagnostic imaging agent used to locate lymph nodes which may be draining from tumors, and assist doctors in locating lymph nodes for removal during surgery.[6]

Technetium (99mTc) tilmanocept
Clinical data
Trade namesLymphoseek
AHFS/Drugs.comMicromedex Detailed Consumer Information
License data
Pregnancy
category
  • AU: C
Routes of
administration
Intradermal, subcutaneous, intratumor
ATC code
Legal status
Legal status
Pharmacokinetic data
Elimination half-life1.75 to 3.05 hours at injection site
Identifiers
IUPAC name
  • Dextran 3-[(2-aminoethyl)thio]propyl 17-carboxy-10,13,16-tris(carboxymethyl)-8-oxo-4-thia-7,10,13,16-tetraazaheptadec-1-yl 3-[[2-[[1-imino-2-(D-mannopyranosylthio)ethyl]amino]ethyl]thio]propyl ether technetium-99m complexes
CAS Number
UNII
KEGG
Chemical and physical data
Formula(C6H10O5)n(C19H28N4O9S99mTc)3–8(C13H24N2O5S2)12–20(C5H11NS)0–17
Molar mass15,281–23,454 g/mol[4]

The most common side effects identified in clinical trials was pain or irritation at the injection site.[7]

It was approved by the U.S. Food and Drug Administration (FDA) in March 2013, for the imaging of lymph nodes.[4][7]

References

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.