Azosemide

Azosemide
Structural formula of azosemide
Space-filling model of the azosemide molecule
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
  • none
Identifiers
IUPAC name
  • 2-chloro-5-(2H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.044.121
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Chemical and physical data
FormulaC12H11ClN6O2S2
Molar mass370.83 g·mol−1
3D model (JSmol)
SMILES
  • O=S(=O)(N)c2c(Cl)cc(c(c1n[nH]nn1)c2)NCc3sccc3
InChI
  • InChI=1S/C12H11ClN6O2S2/c13-9-5-10(15-6-7-2-1-3-22-7)8(12-16-18-19-17-12)4-11(9)23(14,20)21/h1-5,15H,6H2,(H2,14,20,21)(H,16,17,18,19) checkY
  • Key:HMEDEBAJARCKCT-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Azosemide is a high-ceiling loop diuretic agent that was brought to market in 1981 by Boehringer Mannheim.[1][2] As of 2015 it was available as a generic in some Asian countries.[3]


Azosemide has been found as an adulterant in ketamine.[4]

References

  1. ↑ Sittig M (1988). Pharmaceutical Manufacturing Encyclopedia (PDF). Vol. 1. Noyes Publications. p. 122. ISBN 978-0-8155-1144-1. Archived from the original (PDF) on 2007-10-23.
  2. ↑ Bormann D (January 1980). "Diuretics". In Hess HJ (ed.). Annual Reports in Medicinal Chemistry. Vol. 15. Academic Press. pp. 100–105 (101). ISBN 978-0-08-058359-4.
  3. ↑ "International listings for azosemide". Drugs.com. Retrieved 23 July 2015.
  4. ↑ "Drug Checking Report 2011" (PDF). Energy Control. Retrieved 20 January 2022.
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