Buphenine

Buphenine (or nylidrin; trade name Arlidin) is a β2 adrenoreceptor agonist[1] that acts as a vasodilator.[2]

Buphenine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 4-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]propyl}phenol
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.531
Chemical and physical data
FormulaC19H25NO2
Molar mass299.414 g·mol−1
3D model (JSmol)
  • OC(c1ccc(O)cc1)C(NC(C)CCc2ccccc2)C

It was developed as a chemical derivative of oxilofrine, and first reported in the literature in 1950.[3]

See also

References
  1. Mittag TW, Tormay A, Messenger M, Podos SM (February 1985). "Ocular hypotension in the rabbit. Receptor mechanisms of pirbuterol and nylidrin". Invest Ophthalmol Vis Sci. 26 (2): 163–9. PMID 2857689. Archived from the original on 2013-04-15.
  2. Freedman L (1955). "Arlidin: a new vasodilative sympathomimetic drug". Angiology. 6 (1): 52–8. doi:10.1177/000331975500600106. PMID 14350296. S2CID 46317963.
  3. Külz F, Schneider M (1950). "Über neue gefäßerweiternde Sympathomimetika" [On new vasodilative sympathomimetics]. Klin Wochenschr (in German). 28 (31–32): 535–7. doi:10.1007/BF01481535. PMID 14775050.


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