Estradiol propoxyphenylpropionate

Estradiol propoxyphenylpropionate (EPPP), sold under the brand name Durovex, is an estrogen medication and estrogen ester which is no longer marketed.[1] It is the C17β propoxyphenylpropionate (propoxyhydrocinnamate) ester of estradiol.[1] It is a long-acting depot estrogen.[2][3]

Estradiol propoxyphenylpropionate
Clinical data
Trade namesDurovex
Other namesEPPP; Estradiol 17-(4-propoxyphenyl)propanoate; Estradiol p-propoxyhydrocinnamate
Routes of
administration		Intramuscular injection
Drug classEstrogen; Estrogen ester
Identifiers
  • [(8R,9S,13S,14S,17S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-(4-propoxyphenyl)propanoate
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC30H38O4
Molar mass462.630 g·mol−1
3D model (JSmol)
  • CCCOc1ccc(CCC(=O)O[C@H]2CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@]23C)cc1
  • InChI=1S/C30H38O4/c1-3-18-33-23-9-4-20(5-10-23)6-15-29(32)34-28-14-13-27-26-11-7-21-19-22(31)8-12-24(21)25(26)16-17-30(27,28)2/h4-5,8-10,12,19,25-28,31H,3,6-7,11,13-18H2,1-2H3/t25-,26-,27+,28+,30+/m1/s1
  • Key:JNWIUSBBFNMZRQ-BOJCFLQHSA-N

See also

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
  2. Baker AP, Bergman F, Paul KG (April 1967). "Studies of eosinophil granulocytes. 3. Steroid hormones and number of eosinophils in the uterus of the mouse and rat". Acta Endocrinologica. 54 (4): 696–706. doi:10.1530/acta.0.0560221. PMID 6071489.
  3. Åkeson Å, Ehrenberg A (17 May 2014). Structure and Function of Oxidation–Reduction Enzymes: Proceedings of the Wenner-Gren Symposium Held at the Wenner-Gren Center, Stockholm, 23–27 August, 1970. Elsevier. pp. 216–. ISBN 978-1-4831-4755-0.
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