HES6

Transcription cofactor HES-6 is a protein that in humans is encoded by the HES6 gene.[5][6]

HES6
Identifiers
AliasesHES6, C-HAIRY1, HES-6, bHLHb41, bHLHc23, hes family bHLH transcription factor 6
External IDsOMIM: 610331 MGI: 1859852 HomoloGene: 23111 GeneCards: HES6
Orthologs
SpeciesHumanMouse
Entrez

55502

55927

Ensembl

ENSG00000144485

ENSMUSG00000067071

UniProt

Q96HZ4

Q9JHE6

RefSeq (mRNA)

NM_018645
NM_001142853
NM_001282434

NM_019479
NM_001360899
NM_001360900

RefSeq (protein)

NP_001136325
NP_001269363
NP_061115

NP_062352
NP_001347828
NP_001347829

Location (UCSC)Chr 2: 238.24 – 238.24 MbChr 1: 91.34 – 91.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

HES6 has been shown to interact with TLE1.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000144485 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000067071 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bae S, Bessho Y, Hojo M, Kageyama R (Aug 2000). "The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation". Development. 127 (13): 2933–43. doi:10.1242/dev.127.13.2933. PMID 10851137.
  6. "Entrez Gene: HES6 hairy and enhancer of split 6 (Drosophila)".
  7. Gao X, Chandra T, Gratton MO, Quélo I, Prud'homme J, Stifani S, St-Arnaud R (Sep 2001). "HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program". J. Cell Biol. 154 (6): 1161–71. doi:10.1083/jcb.200104058. PMC 2150829. PMID 11551980.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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