ZNF281

ZNF281
Identifiers
Aliases	ZNF281, ZBP-99, ZNP-99, zinc finger protein 281, ZBP99, GZP1
External IDs	MGI: 3029290 HomoloGene: 8270 GeneCards: ZNF281
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	200,410,056 bp[1]
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)[2]
End	136,557,791 bp[2]
RNA expression pattern
	Top expressed in
	secondary oocyte; ; endothelial cell; ; cerebellar vermis; ; Brodmann area 23; ; cancellous bone; ; inferior ganglion of vagus nerve; ; visceral pleura; ; germinal epithelium; ; bone marrow; ; stromal cell of endometrium;
	Top expressed in
	olfactory tubercle; ; ascending aorta; ; maxillary prominence; ; superior cervical ganglion; ; hand; ; aortic valve; ; medial geniculate nucleus; ; substantia nigra; ; globus pallidus; ; subiculum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; transcription corepressor activity; DNA-binding transcription factor activity; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleus;
Biological process	cell differentiation; regulation of transcription, DNA-templated; embryonic body morphogenesis; negative regulation of transcription by RNA polymerase II; negative regulation of gene expression; transcription, DNA-templated; stem cell differentiation; positive regulation of transcription, DNA-templated; negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	23528
	226442
	ENSG00000162702
	ENSMUSG00000041483
	Q9Y2X9
	Q99LI5
	NM_012482; NM_001281293; NM_001281294
	NM_001160251; NM_177643
	NP_001268222; NP_001268223; NP_036614
	NP_001153723; NP_808311
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 281 is a protein that in humans is encoded by the ZNF281 gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000162702 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000041483 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Law DJ, Du M, Law GL, Merchant JL (Sep 1999). "ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression". Biochem Biophys Res Commun. 262 (1): 113–120. doi:10.1006/bbrc.1999.1180. PMID 10448078.
"Entrez Gene: ZNF281 zinc finger protein 281".

External links

ZNF281+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000162702 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041483 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10448078-5] Law DJ, Du M, Law GL, Merchant JL (Sep 1999). "ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression". Biochem Biophys Res Commun. 262 (1): 113–120. doi:10.1006/bbrc.1999.1180. PMID 10448078.

[entrez-6] "Entrez Gene: ZNF281 zinc finger protein 281".

ZNF281

See also

References

Further reading

External links